Roelofs Kelsey, Weis Ezekiel
Department of Ophthalmology and Visual Sciences, University of Alberta, Edmonton, Alberta, Canada.
Department of Surgery, University of Calgary, Calgary, Alberta, Canada.
Ocul Oncol Pathol. 2019 Jun;5(4):298-302. doi: 10.1159/000494977. Epub 2018 Dec 13.
BACKGROUND/AIMS: To evaluate teleophthalmological assessment of choroidal and iris nevi (tele-oncology) compared to traditional in-person clinical evaluation for detection of either axial or basal growth.
This is a validation study. All 97 eyes of 99 patients were evaluated with an in-person ocular oncology visit utilizing standard testing, and subsequently had a tele-oncology evaluation with the standardized tests. The tele-oncology reviewer was blinded to the in-person examination findings. The primary study outcome was detection of nevus growth on tele-oncology compared to in-person clinical examination.
Patients had a mean age of 61 years and the majority had nevi located in the choroid ( = 87; 88%). The most common diagnosis was a low-risk nevus ( = 38; 44%). By tele-oncology assessment, 11 eyes showed growth. Ten of these patients had growth confirmed on in-person clinical examination. Resultantly, tele-oncology assessment of choroidal and iris nevi growth had a sensitivity of 100%, specificity of 99%, positive predictive value (PPV) of 91%, and negative predictive value (NPV) of 100%.
The results of this study suggest that tele-oncology is a safe platform for monitoring choroidal and iris nevi for growth, with excellent sensitivity, specificity, PPV, and NPV.
背景/目的:评估与传统的面对面临床评估相比,远程眼科对脉络膜和虹膜痣(远程肿瘤学)的评估在检测轴向或基底生长方面的效果。
这是一项验证性研究。对99例患者的97只眼睛进行了面对面的眼科肿瘤学检查,采用标准测试,随后进行了标准化测试的远程肿瘤学评估。远程肿瘤学评估人员对面对面检查结果不知情。主要研究结果是与面对面临床检查相比,远程肿瘤学检测到的痣生长情况。
患者的平均年龄为61岁,大多数患者的痣位于脉络膜(n = 87;88%)。最常见的诊断是低风险痣(n = 38;44%)。通过远程肿瘤学评估,11只眼睛显示有生长。其中10例患者在面对面临床检查中证实有生长。因此,远程肿瘤学对脉络膜和虹膜痣生长的评估敏感性为100%,特异性为99%,阳性预测值(PPV)为91%,阴性预测值(NPV)为100%。
本研究结果表明,远程肿瘤学是一个监测脉络膜和虹膜痣生长的安全平台,具有出色的敏感性、特异性、PPV和NPV。