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远程肿瘤学:脉络膜和虹膜痣的验证研究

Tele-Oncology: A Validation Study of Choroidal and Iris Nevi.

作者信息

Roelofs Kelsey, Weis Ezekiel

机构信息

Department of Ophthalmology and Visual Sciences, University of Alberta, Edmonton, Alberta, Canada.

Department of Surgery, University of Calgary, Calgary, Alberta, Canada.

出版信息

Ocul Oncol Pathol. 2019 Jun;5(4):298-302. doi: 10.1159/000494977. Epub 2018 Dec 13.

Abstract

BACKGROUND/AIMS: To evaluate teleophthalmological assessment of choroidal and iris nevi (tele-oncology) compared to traditional in-person clinical evaluation for detection of either axial or basal growth.

METHODS

This is a validation study. All 97 eyes of 99 patients were evaluated with an in-person ocular oncology visit utilizing standard testing, and subsequently had a tele-oncology evaluation with the standardized tests. The tele-oncology reviewer was blinded to the in-person examination findings. The primary study outcome was detection of nevus growth on tele-oncology compared to in-person clinical examination.

RESULTS

Patients had a mean age of 61 years and the majority had nevi located in the choroid ( = 87; 88%). The most common diagnosis was a low-risk nevus ( = 38; 44%). By tele-oncology assessment, 11 eyes showed growth. Ten of these patients had growth confirmed on in-person clinical examination. Resultantly, tele-oncology assessment of choroidal and iris nevi growth had a sensitivity of 100%, specificity of 99%, positive predictive value (PPV) of 91%, and negative predictive value (NPV) of 100%.

CONCLUSIONS

The results of this study suggest that tele-oncology is a safe platform for monitoring choroidal and iris nevi for growth, with excellent sensitivity, specificity, PPV, and NPV.

摘要

背景/目的:评估与传统的面对面临床评估相比,远程眼科对脉络膜和虹膜痣(远程肿瘤学)的评估在检测轴向或基底生长方面的效果。

方法

这是一项验证性研究。对99例患者的97只眼睛进行了面对面的眼科肿瘤学检查,采用标准测试,随后进行了标准化测试的远程肿瘤学评估。远程肿瘤学评估人员对面对面检查结果不知情。主要研究结果是与面对面临床检查相比,远程肿瘤学检测到的痣生长情况。

结果

患者的平均年龄为61岁,大多数患者的痣位于脉络膜(n = 87;88%)。最常见的诊断是低风险痣(n = 38;44%)。通过远程肿瘤学评估,11只眼睛显示有生长。其中10例患者在面对面临床检查中证实有生长。因此,远程肿瘤学对脉络膜和虹膜痣生长的评估敏感性为100%,特异性为99%,阳性预测值(PPV)为91%,阴性预测值(NPV)为100%。

结论

本研究结果表明,远程肿瘤学是一个监测脉络膜和虹膜痣生长的安全平台,具有出色的敏感性、特异性、PPV和NPV。

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Tele-Oncology: A Validation Study of Choroidal and Iris Nevi.远程肿瘤学:脉络膜和虹膜痣的验证研究
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