中国云贵高原原发性肺肝样腺癌：一例报告
Primary hepatoid adenocarcinoma of the lung in Yungui Plateau, China: A case report.
作者信息
Shi Yun-Fei, Lu Jia-Gui, Yang Qing-Mei, Duan Jin, Lei You-Ming, Zhao Wei, Liu Yin-Qiang
机构信息
Department of Thoracic Surgery in the Elderly, the First Affiliated Hospital of Kunming Medical University, Kunming 650032, Yunnan Province, China.
出版信息
World J Clin Cases. 2019 Jul 6;7(13):1711-1716. doi: 10.12998/wjcc.v7.i13.1711.
BACKGROUND
Hepatoid adenocarcinoma (HAC) occurs in extrahepatic organs such as the gastrointestinal tract, testes, ovaries, lungs, mediastinum and pancreas, and frequently produces α-fetoprotein (AFP). HAC of the lung (HAL) is rare, characterized by difficult treatment and poor prognosis. There are no reports of HAL in Yunnan-Guizhou Plateau, China.
CASE SUMMARY
A 60-year-old male patient was clinically diagnosed with HAL pT3N0M0, stage IIB. Chest computed tomography revealed a 7.5 cm × 7.2 cm soft tissue mass located in the right lung upper lobe and the adjacent superior mediastinum. Right upper lobectomy was performed. The diagnosis of HAL was confirmed by pathological examination, and the patient received paclitaxel and carboplatin as adjuvant chemotherapy after surgery.
CONCLUSION
Clinical manifestations, pathological features, imaging findings, auxiliary examination, and treatment planning of HAL are presented to help clinicians improve their diagnosis and treatment.
背景
肝样腺癌（HAC）发生于胃肠道、睾丸、卵巢、肺、纵隔和胰腺等肝外器官，且常产生甲胎蛋白（AFP）。肺肝样腺癌（HAL）罕见，其特点是治疗困难、预后不良。中国云贵高原尚无HAL的报道。
病例摘要
一名60岁男性患者临床诊断为HAL pT3N0M0，ⅡB期。胸部计算机断层扫描显示右肺上叶及相邻上纵隔有一个7.5 cm×7.2 cm的软组织肿块。行右上叶切除术。病理检查确诊为HAL，患者术后接受紫杉醇和卡铂辅助化疗。
结论
介绍HAL的临床表现、病理特征、影像学表现、辅助检查及治疗方案，以帮助临床医生提高其诊断和治疗水平。
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