Yang Jian-Ming, Zhang Wei-Hao, Yang Dan-Dan, Jiang Hao, Yu Lei, Gao Feng
Department of Colorectal Cancer Surgery, Second Affiliated Hospital of Harbin Medical University, Harbin 150000, Heilongjiang Province, China.
World J Clin Cases. 2019 Jul 6;7(13):1726-1731. doi: 10.12998/wjcc.v7.i13.1726.
Appendiceal mucinous neoplasm (AMN) is extremely rare. Since the disease does not manifest a characteristic profile of clinical symptoms, it is easy to misdiagnose and still difficult to diagnose without operation. Here, we report a case of low-grade AMN (LAMN) and summarize its clinical features, diagnosis, and treatment.
A 63-year-old postmenopausal woman presented with a history of right lower abdominal mass. The patient underwent laparotomy, which showed an appendiceal mucocele originating from the apex of the appendix, and a simple appendectomy was performed. The subsequent histological assessment identified an LAMN with no lymph node involvement and negative surgical margin. The patient received six cycles of chemotherapy after surgery, and to date, more than a year after the surgery, the patient remains in good health.
A unified, standardized, detailed, and accurate pathological diagnosis is needed for LAMN, to facilitate selection of an appropriate surgical plan. In addition, the surgeon should record the details of the tumors in the surgical records in order to facilitate follow-up after surgery.
阑尾黏液性肿瘤(AMN)极为罕见。由于该疾病无特征性的临床症状表现,容易误诊,且在未手术的情况下仍难以诊断。在此,我们报告一例低级别AMN(LAMN)病例,并总结其临床特征、诊断及治疗方法。
一名63岁绝经后女性,有右下腹部肿块病史。患者接受了剖腹手术,术中发现一个起源于阑尾尖端的阑尾黏液囊肿,并进行了单纯阑尾切除术。随后的组织学评估确定为LAMN,无淋巴结受累且手术切缘阴性。患者术后接受了六个周期的化疗,截至手术一年多后,患者仍健康状况良好。
LAMN需要统一、规范、详细且准确的病理诊断,以利于选择合适的手术方案。此外,外科医生应在手术记录中记录肿瘤的详细情况,以便于术后随访。