Basic Sciences Department, Preparatory Year Deanship, King Faisal University, Al Hofuf, Saudi Arabia.
Department of Bioinformatics and Medical Engineering, Asia University, Taichung, Taiwan.
J Food Biochem. 2019 Aug;43(8):e12936. doi: 10.1111/jfbc.12936. Epub 2019 Jun 4.
Antrodia cinnamomea or Antrodia camphorata is a distinctive mushroom of Taiwan, which is being used as a traditional medicine to treat various health-related conditions. More than 78 compounds have been identified in A. cinnamomea. Large numbers of phytochemical studies have been carried out in A. cinnamomea due to the high amount of terpenoids. Besides that, the extracts and active components of A. cinnamomea were reported to have various biological activities including hepatoprotective, antihypertensive, antihyperlipidemic, anti-inflammatory, antioxidant, antitumor, and immunomodulatory activities. In this review article, we have summarized the recent findings of A. cinnamomea and its molecular mechanisms of action in various disease models. PRACTICAL APPLICATIONS: A. cinnamomea, medicinal fungus used in traditional medicine in Taiwan also possess high market value. Aim of the present review is to highlight the compounds present in A. cinnamomea and their different pharmacological activities in preventing/cure various diseases/disorders. A. cinnamomea can be potentially developed into health foods or drugs.
樟芝或牛樟芝是台湾特有的一种蘑菇,被用作传统药物来治疗各种与健康相关的疾病。在樟芝中已经鉴定出超过 78 种化合物。由于萜类化合物含量高,对樟芝进行了大量的植物化学研究。此外,樟芝的提取物和活性成分被报道具有多种生物活性,包括保肝、降压、抗高血脂、抗炎、抗氧化、抗肿瘤和免疫调节活性。在这篇综述文章中,我们总结了樟芝的最新研究结果及其在各种疾病模型中的作用机制。实际应用:樟芝,台湾传统医学中使用的药用真菌,也具有很高的市场价值。本综述的目的是强调樟芝中存在的化合物及其在预防/治疗各种疾病/障碍方面的不同药理活性。樟芝可以被开发成保健品或药物。