School of Light Industry, Beijing Technology and Business University (BTBU), Beijing 100048, China.
Molecules. 2023 Mar 29;28(7):3036. doi: 10.3390/molecules28073036.
Selenium (Se) is an essential nutrient element in human physiological metabolism and immune function. Supplementation of bioavailable Se will confer benefit on human life, especially when intake of this nutrient is inadequate. The edible and medicinal mushroom is a unique fungus endemic to Taiwan, which has shown high therapeutic and nutritive value. This study is the first to demonstrate that can assimilate and transform sodium selenite into organic selenium. With an initial concentration of Se (IV) at 10 mg/L in 100 mL of the medium at 25 °C, the total selenium content in Se-enriched mycelia was 1281.3 ± 79.2 µg/g, in which the organic selenium content accounted for 88.1%. Further analysis demonstrated that selenium-enriched polysaccharide was the main form of Se present in (61.5% of the organic selenium). Four water-soluble Se-polysaccharide fractions were separated from , and ACP II was the major fraction of Se-polysaccharide. The scavenging efficiency of Se-polysaccharides on DPPH and ABTS radicals was determined, proving that selenium enrichment dramatically improved the in vitro antioxidant capacity of polysaccharide. Therefore, the selenium accumulation and transformation ability of provides an opportunity for developing this beneficent fungus into a novel selenium-enriched dietary or medicinal supplement.
硒（Se）是人体生理代谢和免疫功能所必需的营养元素。补充生物可利用的硒将有益于人类生命，特别是当这种营养素摄入不足时。药用蘑菇 是台湾特有的一种独特真菌，具有很高的治疗和营养价值。本研究首次证明 可以将亚硒酸钠同化并转化为有机硒。在 25°C 下，初始硒 (IV) 浓度为 100 毫升培养基中的 10 毫克/升，富硒 菌丝体中的总硒含量为 1281.3 ± 79.2 µg/g，其中有机硒含量占 88.1%。进一步分析表明，硒多糖是 中存在的主要硒形式（占有机硒的 61.5%）。从 中分离出四种水溶性硒多糖，ACP II 是硒多糖的主要部分。测定了硒多糖对 DPPH 和 ABTS 自由基的清除效率，证明硒的富集极大地提高了 多糖的体外抗氧化能力。因此， 积累和转化硒的能力为将这种有益真菌开发成新型富硒膳食或药用补充剂提供了机会。
