刘易斯大鼠淋巴细胞再循环的基本机制。
Basic mechanisms of lymphocyte recirculation in Lewis rats.
作者信息
Anderson A O, Anderson N D, White J D
出版信息
Adv Exp Med Biol. 1979;114:73-83. doi: 10.1007/978-1-4615-9101-6_12.
PMID:313688
Abstract
Lymphocyte locomotion in vivo depends upon an intact network of subplasmalemmal contractile microfilaments which are linked through the membrane to surface receptors, and the distribution and stabilization of recognition receptors may be controlled by microtubules and/or 10-nm filaments in the cytoplasm. The differential effects of cytochalasin-A and colchicine on lymphocyte homing and locomotion have proven useful in dissecting the subcellular events underlying the process of lymphocyte recirculation.
摘要
淋巴细胞在体内的移动依赖于完整的膜下收缩性微丝网络，这些微丝通过膜与表面受体相连，识别受体的分布和稳定性可能受细胞质中的微管和/或10纳米细丝控制。细胞松弛素A和秋水仙碱对淋巴细胞归巢和移动的不同作用已被证明有助于剖析淋巴细胞再循环过程中潜在的亚细胞事件。
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