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Attributes influencing parental decision-making to receive the Tdap vaccine to reduce the risk of pertussis transmission to their newborn - outcome of a cross-sectional conjoint experiment in Spain and Italy.影响父母决定接种 Tdap 疫苗以降低新生儿百日咳传播风险的因素 - 西班牙和意大利横断面联合实验的结果。
Hum Vaccin Immunother. 2019;15(5):1080-1091. doi: 10.1080/21645515.2019.1571890. Epub 2019 Apr 15.
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Understanding barriers and predictors of maternal immunization: Identifying gaps through an exploratory literature review.了解孕产妇免疫接种的障碍和预测因素:通过探索性文献综述确定差距。
Vaccine. 2018 Nov 26;36(49):7445-7455. doi: 10.1016/j.vaccine.2018.10.046. Epub 2018 Oct 28.
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Strategies for increasing uptake of vaccination in pregnancy in high-income countries: A systematic review.高收入国家提高孕期疫苗接种率的策略:系统评价。
Vaccine. 2018 May 11;36(20):2751-2759. doi: 10.1016/j.vaccine.2018.04.013. Epub 2018 Apr 13.
4
A case of undiagnosed Bordetella pertussis infection in a neonate.
Pomeranian J Life Sci. 2016;62(2):63-5.
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Questionnaire survey on mumps vaccination for parents in Nara prefecture, Japan.日本奈良县针对家长进行的腮腺炎疫苗接种问卷调查。
Pediatr Int. 2018 Apr;60(4):362-365. doi: 10.1111/ped.13502. Epub 2018 Feb 26.
6
Pertussis epidemiology prior to the introduction of a maternal vaccination program, Queensland Australia.百日咳在引入母体疫苗接种计划前的流行病学情况,澳大利亚昆士兰州。
Epidemiol Infect. 2018 Jan;146(2):207-217. doi: 10.1017/S0950268817002722. Epub 2017 Dec 6.
7
Antenatal vaccination to decrease pertussis in infants: safety, effectiveness, timing, and implementation.产前接种疫苗以降低婴儿百日咳发病率:安全性、有效性、时机及实施情况
J Matern Fetal Neonatal Med. 2019 May;32(9):1541-1546. doi: 10.1080/14767058.2017.1406475. Epub 2017 Dec 3.
8
Efficacy and safety of pertussis vaccination for pregnant women - a systematic review of randomised controlled trials and observational studies.孕妇百白破疫苗接种的有效性和安全性:随机对照试验和观察性研究的系统评价。
BMC Pregnancy Childbirth. 2017 Nov 22;17(1):390. doi: 10.1186/s12884-017-1559-2.
9
Impact of the US Maternal Tetanus, Diphtheria, and Acellular Pertussis Vaccination Program on Preventing Pertussis in Infants <2 Months of Age: A Case-Control Evaluation.美国孕产妇破伤风、白喉和无细胞百日咳疫苗接种计划对预防 2 个月龄以下婴儿百日咳的影响:病例对照评估。
Clin Infect Dis. 2017 Nov 29;65(12):1977-1983. doi: 10.1093/cid/cix724.
10
An update of the global burden of pertussis in children younger than 5 years: a modelling study.全球 5 岁以下儿童百日咳负担的更新:一项建模研究。
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日本奈良县孕妇和产妇百白破疫苗接种情况问卷调查。

Questionnaire survey on maternal pertussis vaccination for pregnant women and mothers in Nara prefecture, Japan.

机构信息

Department of Pediatrics, Nara Medical University, Kashihara-shi, Japan.

出版信息

Hum Vaccin Immunother. 2020;16(2):335-339. doi: 10.1080/21645515.2019.1651000. Epub 2019 Sep 5.

DOI:10.1080/21645515.2019.1651000
PMID:31368853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7062446/
Abstract

: Infantile pertussis is a major concern and causes a significant health burden worldwide. Maternal adult tetanus, diphtheria, and acellular pertussis (Tdap) vaccination is very effective way of preventing infantile pertussis. However, Tdap has not been approved by the Japanese government or been included in Japan's national immunization program (NIP). We carried out a questionnaire survey to investigate whether Japanese women would accept the Tdap vaccination if they were provided with appropriate information.: The questionnaire survey was administered to pregnant women who visited the Obstetrics and Gynecology Department and mothers who visited the Pediatrics Department of Nara Medical University, Kashihara City, Japan, between October 2018 and May 2019. The questionnaire included information about pertussis infection and maternal vaccination, followed by seven questions.: A total of 943 participants answered the questionnaire (481 pregnant women and 462 mothers). Before reading the information, just 4.6% of participants knew that infantile pertussis can be prevented by maternal vaccination. After reading the information, 93.0% and 92.6% of participants thought that the maternal Tdap vaccine should be approved by the Japanese government and be included in the NIP, respectively. Although only 67.6% of participants wished to have the maternal Tdap vaccine without government financial support after reading the information, 92.5% said they would have the vaccine with government support ( < .001).: Most Japanese mothers and pregnant women would like the maternal Tdap vaccine to be approved by the government and included in the NIP, once they have been provided with appropriate information.

摘要

婴儿百日咳是一个重大关注点,在全球范围内造成了巨大的健康负担。母亲接种成人破伤风、白喉和无细胞百日咳(Tdap)疫苗是预防婴儿百日咳的非常有效方法。然而,Tdap 尚未获得日本政府批准,也未被纳入日本国家免疫计划(NIP)。我们进行了一项问卷调查,以调查如果提供适当的信息,日本妇女是否会接受 Tdap 疫苗接种。

该问卷调查于 2018 年 10 月至 2019 年 5 月期间在日本奈良医科大学妇产科和儿科就诊的孕妇和母亲中进行。问卷包括关于百日咳感染和母亲疫苗接种的信息,随后是七个问题。

共有 943 名参与者回答了问卷(481 名孕妇和 462 名母亲)。在阅读信息之前,只有 4.6%的参与者知道婴儿百日咳可以通过母亲接种疫苗来预防。阅读信息后,93.0%和 92.6%的参与者分别认为日本政府应批准母亲 Tdap 疫苗并将其纳入 NIP。尽管只有 67.6%的参与者在阅读信息后希望在没有政府财政支持的情况下接种母亲 Tdap 疫苗,但 92.5%的人表示他们将在政府支持下接种疫苗(<0.001)。

大多数日本母亲和孕妇希望政府批准并将母亲 Tdap 疫苗纳入 NIP,一旦他们获得了适当的信息。