Universidade do Vale do Sapucaí, Pouso Alegre, Brazil.
Microb Drug Resist. 2019 Dec;25(10):1490-1496. doi: 10.1089/mdr.2018.0047. Epub 2019 Aug 1.
Phytotherapy is an emerging topic of health research, with particular focus on studying the efficiency of essential oils as antimicrobials. In this study, we investigated the and susceptibility of strains isolated from newborns to oil. The susceptibility of the microorganisms to essential oil was compared with the activities of standard antibiotics administered to newborns using disk diffusion and microdilution methods. For assessment, 30 Wistar rats were wounded and subjected to infection of strain DRJ080, followed by treatment with the antibiotic vancomycin, , or carbopol polymer gel (control) for 11 days. accounted for 23.36% of the 107 sp. strains isolated. Both vancomycin and the essential oil of inhibited the growth of all microorganisms . The minimum inhibitory and bactericidal concentrations for the oil were 0.625 mg/mL in all strains tested. The oil had the same therapeutic effectiveness as vancomycin against DRJ080 in rats. Thus, strains of newborns are sensitive to oil, both and , demonstrating its potential as an antibiotic alternative.
植物疗法是健康研究中一个新兴的课题，特别侧重于研究精油作为抗菌剂的效率。在这项研究中，我们研究了从新生儿中分离出来的 株对 油的 和 敏感性。使用圆盘扩散和微量稀释法比较了微生物对 精油的敏感性与新生儿使用的标准抗生素的活性。为了评估，将 30 只 Wistar 大鼠受伤，并感染 株 DRJ080，然后用抗生素万古霉素、 或卡波姆聚合物凝胶（对照）治疗 11 天。 占 107 株 分离株的 23.36%。万古霉素和 的精油都抑制了所有微生物的生长 。在所有测试的菌株中， 油的最小抑菌和杀菌浓度均为 0.625 mg/mL。油对大鼠 DRJ080 的治疗效果与万古霉素相同。因此，新生儿的 株对 油敏感，无论是 还是 ，表明其作为抗生素替代品的潜力。
