甲状腺疾病与代谢综合征。
Thyroid disease and the metabolic syndrome.
机构信息
Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
出版信息
Curr Opin Endocrinol Diabetes Obes. 2019 Oct;26(5):256-265. doi: 10.1097/MED.0000000000000500.
PURPOSE OF REVIEW
To summarize recent developments in the association of thyroid function with metabolic syndrome (MetS).
RECENT FINDINGS
Although thyroid hormones even within low normal range are associated with various metabolic abnormalities, the risk of MetS remains a controversial issue. Hyperthyroid state might be associated only with insulin resistance and dysglycemia. Autoimmune thyroid diseases may be a potential risk factor for metabolic abnormalities even in those with low normal thyroid function.
SUMMARY
The interrelation between thyroid stimulating hormone, free T3, freeT4 and metabolic parameters is complex and might be affected by age, sex, BMI, insulin resistance, smoking, iodine intake and inflammatory markers.
目的综述
总结甲状腺功能与代谢综合征（MetS）关联的最新研究进展。
最新发现
尽管甲状腺激素即使在正常低值范围内，也与各种代谢异常有关，但代谢综合征的风险仍是一个有争议的问题。甲状腺功能亢进状态可能仅与胰岛素抵抗和糖代谢异常有关。自身免疫性甲状腺疾病可能是即使甲状腺功能正常低值患者发生代谢异常的潜在危险因素。
总结
促甲状腺激素、游离 T3、游离 T4 与代谢参数之间的相互关系很复杂，可能受年龄、性别、BMI、胰岛素抵抗、吸烟、碘摄入量和炎症标志物的影响。
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