Kim Minju, Sowndhararajan Kandhasamy, Choi Hae Jin, Park Se Jin, Kim Songmun
School of Natural Resources and Environmental Science, Kangwon National University, Chuncheon 24341, Korea.
Department of Botany, Kongunadu Arts and Science College, Coimbatore 641029, India.
Biomedicines. 2019 Jul 31;7(3):57. doi: 10.3390/biomedicines7030057.
Fragrances play a pivotal role in humans' psychological and physiological functions through the olfactory system. Aldehydes are important organic compounds with a variety of fragrance notes. Particularly, nonanal (C9) and decanal (C10) aldehydes are important natural fragrant components used to enhance floral, as well as citrus notes in perfumery products. In general, each nostril of the human nose is tuned to smell certain odor molecules better than others due to slight turbinate swelling between the nostrils. Hence, the objective of the present investigation was aimed to evaluate the influence of binasal and uninasal inhalations of C9 and C10 aldehydes on human electroencephalographic (EEG) activity. Twenty healthy participants (10 males and 10 females) participated in this study. The EEG readings were recorded from 8 electrodes (QEEG-8 system) according to the International 10-20 System. The results revealed that C10 exposure exhibited significantly different EEG changes, during binasal and uninasal inhalations. In different brain regions, C10 odor markedly decreased the absolute alpha and absolute beta power spectra. In regards to C9 odor, significant changes of EEG power spectra were noticed only during binasal inhalation. In addition, C10 mainly produced changes at the left parietal site (P3) than other brain sites. In conclusion, the variations in EEG activities of C9 and C10 aldehydes might be owing to their characteristic fragrance quality, as well as the influence of nostril differences.
香料通过嗅觉系统在人类心理和生理功能中发挥关键作用。醛类是具有多种香味特征的重要有机化合物。特别是壬醛（C9）和癸醛（C10）是重要的天然香料成分，用于增强香水产品中的花香以及柑橘香调。一般来说，由于鼻孔之间轻微的鼻甲肿胀，人类鼻子的每个鼻孔对某些气味分子的嗅觉比其他分子更灵敏。因此，本研究的目的是评估双侧和单侧吸入C9和C10醛对人类脑电图（EEG）活动的影响。20名健康参与者（10名男性和10名女性）参与了这项研究。根据国际10-20系统，从8个电极（定量脑电图-8系统）记录脑电图读数。结果显示，在双侧和单侧吸入过程中，接触C10表现出明显不同的脑电图变化。在不同脑区，C10气味显著降低了绝对α和绝对β功率谱。对于C9气味，仅在双侧吸入时才注意到脑电图功率谱的显著变化。此外，C10主要在左顶叶部位（P3）产生的变化比其他脑部位更多。总之，C9和C10醛的脑电图活动变化可能归因于它们独特的香味品质以及鼻孔差异的影响。
