Pediatric Multiple Sclerosis and Demyelinating Diseases Center, Washington University in St. Louis, St. Louis, Missouri.
Pediatric Multiple Sclerosis and Demyelinating Diseases Center, Washington University in St. Louis, St. Louis, Missouri.
Pediatr Neurol. 2019 Nov;100:26-34. doi: 10.1016/j.pediatrneurol.2019.06.017. Epub 2019 Jul 3.
Acute disseminated encephalomyelitis is an inflammatory disorder of the central nervous system. Uniform diagnostic criteria for acute disseminated encephalomyelitis did not exist until publication of expert-defined consensus definitions by the International Pediatric Multiple Sclerosis Society Group in 2007, with updates in 2013. In the expanding field of pediatric neuroimmunology, consistent diagnostic criteria are essential to correctly categorize patients as increasing information regarding prognosis and management becomes available. Scientific literature is relatively lacking in review articles on International Pediatric Multiple Sclerosis Society Group-defined acute disseminated encephalomyelitis. This review focuses primarily on references applying the International Pediatric Multiple Sclerosis Society Group criteria for acute disseminated encephalomyelitis presenting specific, up-to-date, and translatable information regarding the epidemiology, pathophysiology, clinical features, diagnosis, management, and prognosis of acute disseminated encephalomyelitis in the pediatric population.
急性播散性脑脊髓炎是一种中枢神经系统的炎症性疾病。直到 2007 年国际儿科多发性硬化协会专家组发表了专家定义的共识定义，并在 2013 年进行了更新，才出现了统一的急性播散性脑脊髓炎诊断标准。在儿科神经免疫学不断发展的领域，为了正确分类患者，一致的诊断标准至关重要，因为有关预后和管理的信息越来越多。关于国际儿科多发性硬化协会定义的急性播散性脑脊髓炎的综述文章在科学文献中相对较少。这篇综述主要集中在应用国际儿科多发性硬化协会急性播散性脑脊髓炎标准的参考文献上，这些文献提供了有关儿科人群中急性播散性脑脊髓炎的流行病学、病理生理学、临床特征、诊断、治疗和预后的具体、最新和可翻译的信息。
