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一例罕见的具有皮节型皮肤表现的布鲁氏菌病病例。

A rare case of brucellosis with dermatomal pattern of cutaneous manifestation.

作者信息

Gharebaghi Naser, Mehrno Mojhdeh, Sedokani Amin

机构信息

Department of Infectious Disease, Faculty of Medicine, Urmia University of Medical Science, Urmia, Iran.

Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran.

出版信息

Int Med Case Rep J. 2019 Jul 11;12:223-228. doi: 10.2147/IMCRJ.S203682. eCollection 2019.

Abstract

Brucellosis is a systemic disease which may involve any organ or system of the body, and is listed in the differential diagnosis of many diseases. In spite of described cutaneous involvements, skin manifestations are not common in brucellosis, particularly papulonodular lesions with dermatomal patterns that may overlap with dermatomal skin lesions. This may prevent correct diagnosis and treatment in practice, harming patients' health and leading to financial costs to the health system and patient. In this case, at first, due to left thigh and buttock skin lesions and dermatomal pattern, the patient was diagnosed with infection. After medical treatment and no improvement of lesions, the patient was referred to the infectious clinic with low back pain; magnetic resonance imaging (ordered by a neurosurgeon) suggested infectious spondylodiscitis. At the infectious ward, brucellosis spondylitis was diagnosed and a biopsy was taken from dermatomal lesions. The patient's follow-up after 1, 2, and 3 months revealed that treatment of brucellosis had led to healing of lesions. Surprisingly, the histopathological assessment of the biopsy suggested psoriasis vulgaris. This was a rare case of manifestation of cutaneous brucellosis which could not even be diagnosed by histopathological assessment.

摘要

布鲁氏菌病是一种全身性疾病,可累及身体的任何器官或系统,在许多疾病的鉴别诊断中都有提及。尽管有文献报道过布鲁氏菌病累及皮肤的情况,但皮肤表现在布鲁氏菌病中并不常见,尤其是具有皮节模式的丘疹结节性病变,这种病变可能与皮节性皮肤病变重叠。这可能会在实际中妨碍正确的诊断和治疗,损害患者健康,并给卫生系统和患者带来经济成本。在这个病例中,起初,由于左大腿和臀部皮肤病变以及皮节模式,患者被诊断为感染。经过药物治疗且病变无改善后,患者因腰痛被转诊至感染科门诊;磁共振成像(由神经外科医生开具)提示感染性脊椎椎间盘炎。在感染病房,诊断为布鲁氏菌病性脊柱炎,并从皮节性病变处取了活检。患者在1个月、2个月和3个月后的随访显示,布鲁氏菌病的治疗使病变愈合。令人惊讶的是,活检的组织病理学评估提示为寻常型银屑病。这是一例罕见的皮肤布鲁氏菌病表现病例,甚至通过组织病理学评估也无法确诊。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6461/6635832/ab38a237afb6/IMCRJ-12-223-g0001.jpg

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