Mughal Abdul Razzaq, Tousif Rubina, Alamgir Asif Rashid, Jalal Anjum
Abdul Razzaq Mughal FCPS (Paed Med), FCPS (Paed Card), Department of Pediatric Cardiology, Faisalabad Institute of Cardiology, Faisalabad, Pakistan.
Rubina Tousif FCPS (Paeds Med), Department of Cardiology, Children Hospital Faisalabad, Pakistan.
Pak J Med Sci. 2019 Jul-Aug;35(4):1066-1071. doi: 10.12669/pjms.35.4.878.
To identify the pattern of un-operated grown up congenital heart defects at our tertiary care cardiac institute.
This is a prospective observational study. All un-operated GUCH patients who presented to Faisalabad Institute of Cardiology (FIC) from May 2017 to 30th July 2017 were enrolled. Diagnosis was established on Transthoracic Echocardiography done by dedicated pediatric cardiologist at FIC. The mode of presentation, presenting complaints, type, severity, complications and co-morbid conditions of CHD were recorded.
A total of 200 consecutive patients were enrolled. Mean age was 29.92 ± 11.21 years. There were 104 females (52%) and 96 males (48%). Majority of patients presented in Out-Patient Department (84%) while 16% presented in emergency (n=32). The most common cardiac anomalies were: Atrial Septal Defect (ASD) 41.5% (83), Tetralogy of Fallots (TOF) 42 (21%), Ventricular Septal Defect (VSD) 28 (14%) and Patent ductus arteriosus (PDA) 8 % (16). Cyanotic CHD was present in 43% (86) while TOF was the most common of it. The disease was of moderate complexity in 77.5% patients. Certain complications like Pulmonary hypertension 69(34.5%), Eisenmenger 33(16.5%), Rhythm disturbances 15 (7.5%), Infective endocarditis 5(2.5%) were also present along with co-morbid conditions like coronary artery disease (1.5% and systemic hypertension (2.5%). Dyspnea on exertion (59.5%) followed by cyanosis (41%) were the most common presenting complaints. The most common reason for hospital admission was cardiac signs and symptoms (19.5%) followed by cardiac catheterization (10.5%).
The ASD, TOF, VSD and PDA remain the most common CHD in descending order while pulmonary hypertension, Eisenmenger, heart failure, arrhythmias, infective endocarditis and stroke were the common complications of CHD at this particular age.
确定我们三级心脏专科医院中未接受手术治疗的成年先天性心脏病的模式。
这是一项前瞻性观察性研究。纳入了2017年5月至2017年7月30日期间在费萨拉巴德心脏病学研究所（FIC）就诊的所有未接受手术治疗的成年先天性心脏病患者。由FIC的专业儿科心脏病专家进行经胸超声心动图检查以确诊。记录冠心病的就诊方式、主诉、类型、严重程度、并发症和合并症。
共连续纳入200例患者。平均年龄为29.92±11.21岁。女性104例（52%），男性96例（48%）。大多数患者在门诊就诊（84%），16%在急诊就诊（n = 32）。最常见的心脏异常为：房间隔缺损（ASD）41.5%（83例）、法洛四联症（TOF）42例（21%）、室间隔缺损（VSD）28例（14%）和动脉导管未闭（PDA）8%（16例）。43%（86例）患者存在青紫型先天性心脏病，其中TOF最为常见。77.5%的患者疾病为中度复杂。还存在某些并发症，如肺动脉高压69例（34.5%）、艾森曼格综合征33例（16.5%）、心律失常15例（7.5%）、感染性心内膜炎5例（2.5%），以及合并症如冠状动脉疾病（1.5%）和系统性高血压（2.5%）。劳力性呼吸困难（59.5%）其次是青紫（41%）是最常见的主诉。住院的最常见原因是心脏体征和症状（19.5%），其次是心脏导管检查（10.5%）。
ASD、TOF、VSD和PDA仍然是最常见的先天性心脏病，按降序排列，而肺动脉高压、艾森曼格综合征、心力衰竭、心律失常、感染性心内膜炎和中风是这个特定年龄段先天性心脏病的常见并发症。
