多位点序列分析揭示了俄罗斯萨拉托夫地区的一种新型序列类型。
Multi-locus sequence analysis reveals a novel sequence type of in Saratov Region, Russia.
作者信息
Feodorova V A, Zaitsev S S, Saltykov Y V, Ulyanov S S, Motin V L
机构信息
Laboratory for Molecular Biology and NanoBiotechnology, Federal Research Center for Virology and Microbiology (FRCViM), Branch in Saratov, Saratov, Russia.
Department for Medical Physics, Saratov State University (SSU), Saratov, Russia.
出版信息
New Microbes New Infect. 2019 Jul 3;31:100584. doi: 10.1016/j.nmni.2019.100584. eCollection 2019 Sep.
is the causative agent of a variety of chlamydial infections in humans with a predominantly (up to 80%) asymptomatic course of disease. In this study, a potentially novel sequence type (ST) was detected in an asymptomatic man who has sex with a man among the nine STs revealed in urogenital swabs from individuals with chlamydia ( = 18). Phylogenetically this ST270 clustered separately as a single clade to an ST13-founded group of strains and differed from the latter by a single allele, . This finding emphasizes the importance of careful investigation of individuals with asymptomatic chlamydia infections.
是人类多种衣原体感染的病原体，其疾病进程主要（高达80%）为无症状。在本研究中，在一名与男性发生性行为的无症状男性中检测到一种潜在的新型序列类型（ST），该ST是在衣原体感染者（n = 18）的泌尿生殖拭子中发现的9种STs之一。在系统发育上，这种ST270作为一个单一的分支与以ST13为基础的一组菌株分开聚类，并且与后者仅相差一个等位基因。这一发现强调了对无症状衣原体感染个体进行仔细调查的重要性。
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