联苯胺、4,4”-二氨基三联苯、4-二甲基氨基偶氮苯和4-氰基二甲基苯胺致突变性的计算机自动预测：与英国环境诱变学会第二次协作研究结果的比较
Computer-automated prediction of the mutagenicity of benzidine, 4,4"-diaminoterphenyl, 4-dimethylaminoazobenzene and 4-cyanodimethylaniline: comparison with the results of the Second UKEMS Collaborative Study.
作者信息
Rosenkranz H S, Frierson M R, Klopman G
机构信息
Department of Environmental Health Sciences, Case Western Reserve University, Cleveland, OH 44106.
出版信息
Mutagenesis. 1986 Jul;1(4):275-82. doi: 10.1093/mutage/1.4.275.
PMID:3137412
Abstract
There was agreement between the experimental results, obtained in the course of the Second UKEMS Collaborative Study, for the mutagenicity in Salmonella typhimurium of benzidine, 4,4"-diaminoterphenyl, 4-dimethylaminoazobenzene and 4-cyanodimethylaniline and the mutagenicity predicted by CASE (Computer Automated Structure Evaluation), a recently developed artificial intelligence system.
摘要
在第二次英国环境诱变剂学会合作研究过程中获得的实验结果，与最近开发的人工智能系统CASE（计算机自动结构评估）预测的联苯胺、4,4”-二氨基联苯、4-二甲基氨基偶氮苯和4-氰基二甲基苯胺在鼠伤寒沙门氏菌中的诱变性之间存在一致性。
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