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Computer-automated prediction of the mutagenicity of benzidine, 4,4"-diaminoterphenyl, 4-dimethylaminoazobenzene and 4-cyanodimethylaniline: comparison with the results of the Second UKEMS Collaborative Study.

作者信息

Rosenkranz H S, Frierson M R, Klopman G

机构信息

Department of Environmental Health Sciences, Case Western Reserve University, Cleveland, OH 44106.

出版信息

Mutagenesis. 1986 Jul;1(4):275-82. doi: 10.1093/mutage/1.4.275.

Abstract

There was agreement between the experimental results, obtained in the course of the Second UKEMS Collaborative Study, for the mutagenicity in Salmonella typhimurium of benzidine, 4,4"-diaminoterphenyl, 4-dimethylaminoazobenzene and 4-cyanodimethylaniline and the mutagenicity predicted by CASE (Computer Automated Structure Evaluation), a recently developed artificial intelligence system.

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