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大咯血的处理

Managing Massive Hemoptysis.

机构信息

Division of Pulmonary and Critical Care Medicine, Virginia Commonwealth University Medical Center, Richmond, VA.

Division of Pulmonary and Critical Care Medicine, Virginia Commonwealth University Medical Center, Richmond, VA.

出版信息

Chest. 2020 Jan;157(1):77-88. doi: 10.1016/j.chest.2019.07.012. Epub 2019 Jul 30.

Abstract

Massive hemoptysis is a medical emergency with high mortality presenting several difficult diagnostic and therapeutic challenges. The origin of bleeding and underlying etiology often is not immediately apparent, and techniques for management of this dangerous condition necessitate an expedient response. Unlike hemorrhage in other circumstances, a small amount of blood can rapidly flood the airways, thereby impairing oxygenation and ventilation, leading to asphyxia and consequent cardiovascular collapse. Of paramount importance is early control of the patient's airway and immediate isolation of hemorrhage in an attempt to localize and control bleeding. A coordinated team response is essential to guarantee the best chances of patient survival. Prompt control of the airway and steps to limit the spread of hemorrhage take precedence. Bronchial artery embolization, rigid and flexible bronchoscopy, and surgery all serve as potential treatment options to provide definitive control of hemorrhage. Several adjunctive therapies described in recent years may also assist in the control of bleeding; however, their role is less defined in life-threatening hemoptysis and warrants additional studies. In this concise review, we emphasize the steps necessary for a systematic approach in the management of life-threatening hemoptysis.

摘要

大咯血是一种具有高死亡率的医学急症,存在许多诊断和治疗方面的难题。出血的来源和潜在病因通常并不立即显现,而管理这种危险情况的技术需要迅速做出反应。与其他情况下的出血不同,少量血液可能会迅速充斥气道,从而损害氧合和通气,导致窒息和随后的心脑血管衰竭。至关重要的是早期控制患者的气道,并立即隔离出血,以试图定位和控制出血。协调的团队反应对于保证患者生存的最佳机会至关重要。迅速控制气道和限制出血扩散的措施至关重要。支气管动脉栓塞、硬镜和软镜检查以及手术都是提供出血控制的潜在治疗选择。近年来描述的几种辅助治疗方法也可能有助于控制出血;然而,在危及生命的大咯血中,它们的作用还不太明确,需要进一步的研究。在这篇简明的综述中,我们强调了在危及生命的大咯血管理中进行系统处理所需的步骤。

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