Gulkarov Iosif, Wong Brian, Kowalski Marcin, Worku Berhane, Afzal Ashwad, Ivanov Alexander, Ramasubbu Kumudha, Reddy Bharath
Department of Cardiothoracic Surgery, Staten Island University Hospital, Staten Island, New York.
Department of Cardiovascular and Thoracic Surgery, Hofstra Northwell School of Medicine, Manhasset, New York.
J Card Surg. 2019 Oct;34(10):1037-1043. doi: 10.1111/jocs.14204. Epub 2019 Aug 2.
Endocardial catheter ablation has been shown to be effective in patients with paroxysmal atrial fibrillation (AF), and significantly less effective in patients with persistent AF (PAF). Lately, there is a trend toward a hybrid approach in the treatment of PAF that may be a more durable treatment for patients with PAF. In this manuscript we report our experience with the convergent ablation procedure in a PAF cohort.
This is a single center retrospective analysis of 31 patients with PAF who underwent the convergent procedure. All patients underwent surgical epicardial ablation of the posterior left atrial through a subxiphoid approach, followed by radiofrequency endocardial ablations on the same day. Patients were followed at 6 months intervals with static electrocardiograms or implanted devices.
Sinus rhythm was achieved intraoperatively in all patients. Recurrence was defined according to Hearlt Rhythm Society definitions. At a median follow up of 17.7 months (IQR 11-24), the recurrence of atrial tachyarrhythmia (AF and atrial flutter) by Kaplan-Meier event free survival analysis occurred in 9 (29%) patients at 1-year follow up and 15 (48%) patients at 2-year follow up with or without the use of antiarrhythmic drugs. Recurrence of AF alone occurred in 4 (13%) patients at 1-year follow up and 9 (29%) patients at 2-year follow up patients. Complication rate in perioperative period was 12.9%.
Our experience showed the hybrid procedure is a relatively safe and effective option for patients with PAF. Further studies are needed to better determine its long-term outcomes.
心内膜导管消融术已被证明对阵发性心房颤动(AF)患者有效,而对持续性房颤(PAF)患者的疗效则明显较差。最近,在PAF治疗中有一种采用混合方法的趋势,这种方法可能对PAF患者是一种更持久的治疗方法。在本手稿中,我们报告了我们在PAF队列中进行融合消融手术的经验。
这是一项对31例行融合手术的PAF患者的单中心回顾性分析。所有患者均通过剑突下途径进行左心房后壁的心外膜消融,然后在同一天进行射频心内膜消融。患者每隔6个月进行静态心电图或植入设备随访。
所有患者术中均实现窦性心律。复发根据心脏节律学会的定义确定。在中位随访17.7个月(四分位间距11 - 24)时,通过Kaplan-Meier无事件生存分析,1年随访时9例(29%)患者出现房性快速心律失常(AF和房扑)复发,2年随访时15例(48%)患者复发,无论是否使用抗心律失常药物。仅AF复发在1年随访时发生于4例(13%)患者,2年随访时发生于9例(29%)患者。围手术期并发症发生率为12.9%。
我们的经验表明,混合手术对于PAF患者是一种相对安全有效的选择。需要进一步研究以更好地确定其长期疗效。