快速眼动睡眠行为障碍中的精准医学

Precision Medicine in Rapid Eye Movement Sleep Behavior Disorder.

作者信息

Högl Birgit, Santamaria Joan, Iranzo Alex, Stefani Ambra

机构信息

Department of Neurology, Medical University of Innsbruck, Anichstrasse 35, Innsbruck 6020, Austria.

Neurology Service, Multidisciplinary Sleep Unit, Hospital Clinic de Barcelona, Institut D'Investigacions Biomèdiques August Pi i Sunyer, Centro de Investigacion Biomedica en Red de Enfermedades Neurodegenerativas, Calle Villarroel, 170, Barcelona 08036, Spain.

出版信息

Sleep Med Clin. 2019 Sep;14(3):351-362. doi: 10.1016/j.jsmc.2019.04.003. Epub 2019 Jun 21.

DOI:10.1016/j.jsmc.2019.04.003

PMID:31375203

Abstract

In recent years, the diagnostic approach to rapid eye movement (REM) sleep behavior disorder (RBD) has become more objective and accurate. This was achieved mainly by introduction of methods to exactly quantify electromyographic (EMG) activity in various muscles during REM sleep. The most established muscle combination for RBD diagnosis is the mentalis and upper extremity EMG. Computer-assisted systems for this analysis have been described, and an increasing number of studies looked into analysis of video events. Recently, prodromal phases of isolated RBD have been recognized.

摘要

近年来，快速眼动（REM）睡眠行为障碍（RBD）的诊断方法变得更加客观和准确。这主要是通过引入精确量化REM睡眠期间各种肌肉肌电图（EMG）活动的方法来实现的。用于RBD诊断的最成熟的肌肉组合是颏肌和上肢EMG。已经描述了用于这种分析的计算机辅助系统，并且越来越多的研究着眼于视频事件的分析。最近，已经认识到孤立性RBD的前驱期。