Centro de Pesquisa Católica do Brasil, Brasilia, Brazil.
Tufts Medical Center, Boston, MA, USA.
J Clin Densitom. 2019 Oct-Dec;22(4):484-488. doi: 10.1016/j.jocd.2019.07.005. Epub 2019 Jul 10.
Vertebral fracture (VF) is the most common type of osteoporotic fracture. VFs are associated with a decline in quality of life and high morbidity and mortality. The presence of a VF is a significant risk factor for developing another fracture; however, most VFs are not clinically recognized and diagnosed. Vertebral fracture assessment by dual-energy X-ray absorptiometry is a low cost, low radiation, convenient, and reliable method to identify VFs. The finding of a previously unrecognized VF may change the assessment of fracture risk, diagnostic classification, and treatment strategies. Vertebral fracture assessment or radiographic lateral spine imaging should be repeated in patients with continued high risk for fracture (e.g., historical height loss >4 cm [>1.5 inches], self-reported but undocumented vertebral fracture, or glucocorticoid therapy equivalent to ≥5 mg of prednisone or equivalent per day for greater than or equal to 3 months).
椎体骨折（VF）是最常见的骨质疏松性骨折类型。VF 与生活质量下降以及高发病率和死亡率有关。存在 VF 是发生另一次骨折的重要危险因素；然而，大多数 VF 并未得到临床识别和诊断。双能 X 射线吸收法（DXA）进行的椎体骨折评估是一种低成本、低辐射、方便且可靠的方法，可用于识别 VF。先前未被识别的 VF 的发现可能会改变骨折风险评估、诊断分类和治疗策略。对于持续存在高骨折风险的患者（例如，既往身高损失 >4 厘米[>1.5 英寸]、自述但无记录的椎体骨折，或糖皮质激素治疗等效于泼尼松≥5 毫克/天或等效物持续时间大于或等于 3 个月），应重复进行椎体骨折评估或放射学侧位脊柱成像。
