透析依赖型癌症患者的免疫治疗：我们对转移性肾细胞癌患者的经验及文献综述。 - Suppr

Immunotherapy in Dialysis-Dependent Cancer Patients: Our Experience in Patients With Metastatic Renal Cell Carcinoma and a Review of the Literature.

作者信息

Vitale Maria Giuseppa, Baldessari Cinzia, Milella Michele, Buti Sebastiano, Militello Anna Maria, Di Girolamo Stefania, Fornarini Giuseppe, Perri Gino, Basso Umberto, Maruzzo Marco, Porta Camillo, Cosmai Laura, Pipitone Stefania, Cerma Krisida, Cascinu Stefano, Sabbatini Roberto

机构信息

Department of Oncology and Haematology, Modena University Hospital, Modena, Italy.

出版信息

Clin Genitourin Cancer. 2019 Oct;17(5):e903-e908. doi: 10.1016/j.clgc.2019.06.009. Epub 2019 Jul 8.

DOI:10.1016/j.clgc.2019.06.009

PMID:31375351

Abstract

摘要

相似文献

Immunotherapy in Dialysis-Dependent Cancer Patients: Our Experience in Patients With Metastatic Renal Cell Carcinoma and a Review of the Literature.透析依赖型癌症患者的免疫治疗：我们对转移性肾细胞癌患者的经验及文献综述。

Clin Genitourin Cancer. 2019 Oct;17(5):e903-e908. doi: 10.1016/j.clgc.2019.06.009. Epub 2019 Jul 8.

Outcomes and Safety of Biweekly and Monthly Nivolumab in Patients with Metastatic Renal Cell Carcinoma and Dialysis: Three Case Reports and Literature Review.接受透析的转移性肾细胞癌患者中每两周和每月使用纳武利尤单抗的疗效和安全性：三例病例报告和文献复习。

Urol Int. 2020;104(3-4):323-326. doi: 10.1159/000504515. Epub 2020 Jan 8.

Immunogenomics of Metastatic Clear-Cell Renal Cell Carcinoma: Remarkable Response to Nivolumab in a Patient With a Pathogenic Germ Line BRCA1 Mutation.转移性透明细胞肾细胞癌的免疫基因组学：一名携带致病性种系BRCA1突变患者对纳武单抗的显著反应。

Clin Genitourin Cancer. 2019 Oct;17(5):e909-e912. doi: 10.1016/j.clgc.2019.06.013. Epub 2019 Jul 11.

Fatal Acute Motor Axonal Neuropathy Induced by Nivolumab: A Case Report and Literature Review.纳武单抗诱发的致死性急性运动轴索性神经病：一例报告及文献综述

Clin Genitourin Cancer. 2019 Dec;17(6):e1104-e1107. doi: 10.1016/j.clgc.2019.07.020. Epub 2019 Aug 5.

Real-world efficacy and safety of nivolumab in previously-treated metastatic renal cell carcinoma, and association between immune-related adverse events and survival: the Italian expanded access program.纳武利尤单抗治疗既往治疗转移性肾细胞癌的真实世界疗效和安全性，以及免疫相关不良事件与生存的关系：意大利扩大准入计划。

J Immunother Cancer. 2019 Apr 3;7(1):99. doi: 10.1186/s40425-019-0579-z.

Safety and Efficacy of Nivolumab in Patients With Metastatic Renal Cell Carcinoma and End-stage Renal Disease at 2 Centers.尼伏鲁单抗在 2 家中心的转移性肾细胞癌和终末期肾病患者中的安全性和疗效。

Clin Genitourin Cancer. 2019 Aug;17(4):e772-e778. doi: 10.1016/j.clgc.2019.04.004. Epub 2019 Apr 17.

Eruptive keratoacanthomas secondary to nivolumab immunotherapy.纳武单抗免疫治疗继发的爆发性角化棘皮瘤

Int J Dermatol. 2018 Mar;57(3):e28-e29. doi: 10.1111/ijd.13893. Epub 2018 Jan 10.

[A CASE OF RENAL CELL CARCINOMA THAT ONCE NIVOLUMAB HAD BEEN EFFECTIVE IN METASTATIC LESION AND MADE PRIMARY TUMOR RESECTABLE].[一例肾细胞癌，纳武单抗曾对转移灶有效并使原发肿瘤可切除]

Nihon Hinyokika Gakkai Zasshi. 2019;110(1):32-35. doi: 10.5980/jpnjurol.110.32.

A case of complete response to nivolumab after long-term progression-free survival with tyrosine kinase inhibitor.酪氨酸激酶抑制剂治疗后长期无进展生存并完全缓解 1 例

Anticancer Drugs. 2018 Oct;29(9):911-913. doi: 10.1097/CAD.0000000000000663.

Fatal fulminant hepatitis induced by combined ipilimumab and nivolumab therapy despite favorable histologic response and confirmed by autopsy in a patient with clear cell renal cell carcinoma.尽管在透明细胞肾细胞癌患者中，组织学反应良好且经尸检证实，但联合使用依匹单抗和纳武利尤单抗治疗仍导致致命性暴发性肝炎。

Immunol Med. 2021 Jun;44(2):136-141. doi: 10.1080/25785826.2020.1788229. Epub 2020 Jul 7.

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Pembrolizumab Plus Lenvatinib for Metastatic Renal Cell Carcinoma in a Patient on Hemodialysis.帕博利珠单抗联合乐伐替尼治疗一名接受血液透析的转移性肾细胞癌患者。

IJU Case Rep. 2025 Mar 9;8(3):223-226. doi: 10.1002/iju5.70011. eCollection 2025 May.

Integrating International Consensus Guidelines for Anticancer Drug Dosing in Kidney Dysfunction (ADDIKD) into everyday practice.将《国际肾功能不全患者抗癌药物剂量共识指南》（ADDIKD）融入日常实践。

EClinicalMedicine. 2025 Mar 25;82:103161. doi: 10.1016/j.eclinm.2025.103161. eCollection 2025 Apr.

Combined standard immunosuppression and immune checkpoint inhibition for BKPyV+ metastatic renal cell carcinoma of the graft in a kidney transplant recipient with chronic rejection: a case report.肾移植受者慢性排斥反应合并BK多瘤病毒阳性移植物转移性肾细胞癌的标准免疫抑制与免疫检查点抑制联合治疗：1例报告

Front Oncol. 2025 Mar 17;15:1506324. doi: 10.3389/fonc.2025.1506324. eCollection 2025.

Interfering with the Expression of Ubiquitin-Like with PHD and Ring Finger Domains 1 Can Inhibit the Invasion of Human Renal Cell Carcinoma.干扰含有 PH 结构域和环指结构域的泛素样蛋白 1 的表达可以抑制人肾细胞癌的侵袭。

Comput Math Methods Med. 2022 May 18;2022:6971131. doi: 10.1155/2022/6971131. eCollection 2022.

Systemic Treatment for Gynecological Cancer Patients Undergoing Hemodialysis.接受血液透析的妇科癌症患者的全身治疗。

Onco Targets Ther. 2023 Jul 8;16:545-558. doi: 10.2147/OTT.S419445. eCollection 2023.

Immune Checkpoint Inhibitors and the Kidney: A Focus on Diagnosis and Management for Personalised Medicine.免疫检查点抑制剂与肾脏：聚焦个性化医疗的诊断与管理

Cancers (Basel). 2023 Mar 21;15(6):1891. doi: 10.3390/cancers15061891.

Comparison of Outcomes Between Therapeutic Combinations Based on Immune Checkpoint Inhibitors or Tyrosine Kinase Inhibitor Monotherapy for First-Line Therapy of Patients with Advanced Renal Cell Carcinoma Outside of Clinical Trials: A Real-World Retrospective Multi-Institutional Study.基于免疫检查点抑制剂或酪氨酸激酶抑制剂单药治疗的联合疗法用于晚期肾细胞癌患者一线治疗的疗效比较：一项非临床试验环境下的真实世界回顾性多机构研究

Target Oncol. 2023 Mar;18(2):209-220. doi: 10.1007/s11523-023-00956-8. Epub 2023 Mar 21.

Treatment of Unresectable Cutaneous Squamous Cell Carcinoma with Cemiplimab in a Patient on Dialysis.使用西米普利单抗治疗一名接受透析患者的不可切除皮肤鳞状细胞癌

Case Rep Oncol. 2023 Mar 3;16(1):137-142. doi: 10.1159/000528414. eCollection 2023 Jan-Dec.

Renal Toxicities in Cancer Patients Receiving Immune-Checkpoint Inhibitors: A Meta-Analysis.接受免疫检查点抑制剂治疗的癌症患者的肾毒性：一项荟萃分析。

J Clin Med. 2022 Jul 27;11(15):4373. doi: 10.3390/jcm11154373.

Immunotherapy and the Spectrum of Kidney Disease: Should We Individualize the Treatment?免疫疗法与肾病谱：我们是否应该个体化治疗？

Front Med (Lausanne). 2022 Jun 14;9:906565. doi: 10.3389/fmed.2022.906565. eCollection 2022.

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Immunotherapy in Dialysis-Dependent Cancer Patients: Our Experience in Patients With Metastatic Renal Cell Carcinoma and a Review of the Literature.

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