Doubling down on siRNAs in the brain.
作者信息
Davidson Beverly L
机构信息
The Raymond G. Perelman Center for Cellular and Molecular Therapeutics, the Children's Hospital of Philadelphia, and the Department of Pathology and Laboratory Medicine, The University of Pennsylvania, Philadelphia, PA, USA.
出版信息
Nat Biotechnol. 2019 Aug;37(8):865-866. doi: 10.1038/s41587-019-0204-1.
PMID:31375811
Abstract
摘要
相似文献
1
Doubling down on siRNAs in the brain.在大脑中加倍使用小干扰RNA。
Nat Biotechnol. 2019 Aug;37(8):865-866. doi: 10.1038/s41587-019-0204-1.
2
Demystifying small RNA pathways.解读小RNA通路
Dev Cell. 2006 Apr;10(4):419-24. doi: 10.1016/j.devcel.2006.03.005.
3
miRNA and shRNA expression vectors based on mRNA and miRNA processing.基于mRNA和miRNA加工的miRNA和shRNA表达载体。
Methods Mol Biol. 2013;936:195-207. doi: 10.1007/978-1-62703-083-0_16.
4
Novel expression vectors enabling induction of gene expression by small-interfering RNAs and microRNAs.能够通过小分子干扰RNA和微小RNA诱导基因表达的新型表达载体。
PLoS One. 2014 Dec 16;9(12):e115327. doi: 10.1371/journal.pone.0115327. eCollection 2014.
5
MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms.微小RNA和小干扰RNA可通过类似机制抑制信使核糖核酸的表达。
Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9779-84. doi: 10.1073/pnas.1630797100. Epub 2003 Aug 5.
6
RNAi and the P-body connection.RNA干扰与P小体的联系。
Nat Cell Biol. 2005 Jul;7(7):643-4. doi: 10.1038/ncb0705-643.
7
Control of translation and mRNA degradation by miRNAs and siRNAs.微小RNA（miRNA）和小干扰RNA（siRNA）对翻译和信使核糖核酸（mRNA）降解的调控
Genes Dev. 2006 Mar 1;20(5):515-24. doi: 10.1101/gad.1399806.
8
siRNAs can function as miRNAs.小干扰RNA可以发挥微小RNA的功能。
Genes Dev. 2003 Feb 15;17(4):438-42. doi: 10.1101/gad.1064703.
9
RNA silencing: small RNAs as ubiquitous regulators of gene expression.RNA沉默：作为基因表达普遍调节因子的小RNA
Curr Opin Plant Biol. 2002 Oct;5(5):444-51. doi: 10.1016/s1369-5266(02)00291-1.
10
RNA-based recognition and targeting: sowing the seeds of specificity.基于 RNA 的识别和靶向：播下特异性的种子。
Nat Rev Mol Cell Biol. 2017 Apr;18(4):215-228. doi: 10.1038/nrm.2016.174. Epub 2017 Feb 15.
引用本文的文献
1
Using nanotechnology to deliver biomolecules from nose to brain - peptides, proteins, monoclonal antibodies and RNA.利用纳米技术将生物分子从鼻腔递送到大脑 - 肽、蛋白质、单克隆抗体和 RNA。
Drug Deliv Transl Res. 2022 Apr;12(4):862-880. doi: 10.1007/s13346-021-01086-2. Epub 2021 Nov 3.
2
Hyperspectral Image Classification Using Deep Genome Graph-Based Approach.基于深度基因组图的高光谱图像分类。
Sensors (Basel). 2021 Sep 28;21(19):6467. doi: 10.3390/s21196467.
3
Advances in the Design of (Nano)Formulations for Delivery of Antisense Oligonucleotides and Small Interfering RNA: Focus on the Central Nervous System.用于递送反义寡核苷酸和小干扰 RNA 的（纳米）制剂设计的进展：聚焦于中枢神经系统。
Mol Pharm. 2021 Apr 5;18(4):1491-1506. doi: 10.1021/acs.molpharmaceut.0c01238. Epub 2021 Mar 18.
Zotero 插件