Herbert Carrie E, Leshko Jenny, Morelli Dawn, Amankwah Ernest, Hanson Jade, Stapleton Gary E
Johns Hopkins All Children's Heart Institute, St. Petersburg, Florida, USA.
Baylor College of Medicine, Texas Children's Hospital, 6651 Main Street Suite 1920, Houston, TX, 77025, USA.
Pediatr Cardiol. 2019 Oct;40(7):1523-1529. doi: 10.1007/s00246-019-02179-z. Epub 2019 Aug 2.
Acute femoral artery occlusion is common in pediatric patients following cardiac catheterization. A variety of means are utilized to assess lower extremity (LE) perfusion and arterial patency following cardiac catheterization including palpation of pulses, pulse oximetry, subjective assessment of lower extremity color and temperature, and ultrasound. We sought to evaluate the utility of Near-Infrared Spectroscopy (NIRS) to monitor LE perfusion in pediatric patients undergoing cardiac catheterization. INVOS pediatric sensors were placed on bilateral LE in all pediatric patients ≤ 40 kg undergoing cardiac catheterization. Data were recorded continuously from the start of the procedure until 4-6 h after completion of the procedure. NIRS readings were compared between the accessed versus non-accessed LE at baseline before start of case, time of vascular access, arterial sheath exchange when applicable, sheath withdrawal, and Safeguard application, deflation, and removal. 133 patients underwent 152 catheterizations with mean age 2.4 ± 2.3 years and mean weight 12.4 ± 13.2 kg. NIRS oximetry readings were significantly decreased in the LE with arterial access compared to non-accessed LE from time of sheath insertion until removal of the pressure assist device post procedure. A greater difference was noted in smaller patients. NIRS oximetry readings did not correlate with subjective assessment of lower extremity perfusion after arterial sheaths were removed. One patient had pulse loss 4 h post procedure with a decrease in oximetry readings noted at this point on review. Weight-based heparin protocol was initiated, and a gradual improvement in oximetry readings was noted over the next 5 h. Vascular ultrasound 12 h later showed no evidence of arterial thrombus. NIRS may be helpful in identifying patients who are risk for developing arterial thrombus post cardiac catheterization and for monitoring response to therapy; however, further study in these patients is warranted.
急性股动脉闭塞在小儿心脏导管插入术后的患者中很常见。心脏导管插入术后,人们采用多种方法评估下肢(LE)灌注和动脉通畅情况,包括触诊脉搏、脉搏血氧饱和度测定、对下肢颜色和温度的主观评估以及超声检查。我们试图评估近红外光谱(NIRS)在监测接受心脏导管插入术的小儿患者LE灌注方面的效用。在所有体重≤40 kg接受心脏导管插入术的小儿患者双侧LE上放置INVOS小儿传感器。从手术开始直至手术结束后4 - 6小时持续记录数据。在病例开始前的基线、血管穿刺时、适用时的动脉鞘更换、鞘拔出、应用保护装置、放气和移除时,比较穿刺侧与未穿刺侧LE的NIRS读数。133例患者接受了152次导管插入术检查,平均年龄2.4±2.3岁,平均体重12.4±13.2 kg。从鞘插入时起直至术后压力辅助装置移除,与未穿刺侧LE相比,穿刺侧LE的NIRS血氧饱和度读数显著降低。在较小的患者中差异更明显。动脉鞘移除后,NIRS血氧饱和度读数与下肢灌注的主观评估不相关。1例患者术后4小时出现脉搏消失,复查时此时血氧饱和度读数下降。启动了基于体重的肝素方案,在接下来的5小时内血氧饱和度读数逐渐改善。12小时后的血管超声检查未显示动脉血栓迹象。NIRS可能有助于识别心脏导管插入术后有发生动脉血栓风险的患者以及监测治疗反应;然而,有必要对这些患者进行进一步研究。