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3D 迭代重建的作用远不止降低剂量。

3D iterative reconstruction can do so much more than reduce dose.

机构信息

Cardiovascular Imaging Technologies, 4320 Wornall Road Suite 114, Kansas City, MO, 64111, USA.

出版信息

J Nucl Cardiol. 2021 Dec;28(6):2633-2637. doi: 10.1007/s12350-019-01827-4. Epub 2019 Aug 2.

DOI:10.1007/s12350-019-01827-4
PMID:31376003
Abstract

Recent advances in software and hardware for cardiac SPECT have the potential to revolutionize nuclear cardiology. It is easy to use these technologies to maintain the status quo and lower radiation dose, despite the fact there is very little evidence that lowering patient dose in already low dose imaging protocols confers any benefit to patients. Cardiac SPECT has tremendous potential for risk stratification, molecular tracers, and high temporal resolution management of patients with electrophysiological disorders. In addition, these new reconstruction techniques can offer spatial resolution that is comparable and sometimes even superior to PET. Lastly, recent research has also held out the potential for performing absolute blood flow qualification using SPECT instrumentation. As these new technologies become available, the goal should be to make images better and improve patient care first, then optimize the dose.

摘要

心脏 SPECT 的软件和硬件的最新进展有可能彻底改变核医学。尽管几乎没有证据表明在已经低剂量成像方案中降低患者剂量会给患者带来任何益处,但使用这些技术来维持现状和降低辐射剂量是很容易的。心脏 SPECT 在风险分层、分子示踪剂以及电生理障碍患者的高时间分辨率管理方面具有巨大潜力。此外,这些新的重建技术可以提供与 PET 相当甚至有时更优的空间分辨率。最后,最近的研究还为使用 SPECT 仪器进行绝对血流定性提供了可能性。随着这些新技术的出现,目标应该是首先使图像更好,改善患者护理,然后优化剂量。

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J Nucl Cardiol. 2013 Oct;20(5):891-907. doi: 10.1007/s12350-013-9760-9.

引用本文的文献

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Employing Multiple Low-Dose PET Images (at Different Dose Levels) as Prior Knowledge to Predict Standard-Dose PET Images.利用多次低剂量 PET 图像(在不同剂量水平)作为先验知识来预测标准剂量 PET 图像。
J Digit Imaging. 2023 Aug;36(4):1588-1596. doi: 10.1007/s10278-023-00815-y. Epub 2023 Mar 29.

本文引用的文献

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Perfusion artifacts caused by marked RV enlargement.显著右心室扩大引起的灌注伪影。
J Nucl Cardiol. 2020 Oct;27(5):1834-1836. doi: 10.1007/s12350-019-01757-1. Epub 2019 May 30.
2
Optimization of SPECT Measurement of Myocardial Blood Flow with Corrections for Attenuation, Motion, and Blood Binding Compared with PET.与PET相比,通过衰减、运动和血液结合校正优化心肌血流的SPECT测量
J Nucl Med. 2017 Dec;58(12):2013-2019. doi: 10.2967/jnumed.117.191049. Epub 2017 Jun 13.
3
Evidence for formation of DNA repair centers and dose-response nonlinearity in human cells.
在人类细胞中形成 DNA 修复中心和剂量反应非线性的证据。
Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):443-8. doi: 10.1073/pnas.1117849108. Epub 2011 Dec 19.