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Is there a role for type 2 CD8 T cells in patients with steroid-resistant asthma?

作者信息

Gelfand Erwin W, Hinks Timothy S C

机构信息

Division of Cell Biology, Department of Pediatrics, National Jewish Health, Denver, Colo.

Respiratory Medicine Unit and National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), Nuffield Department of Medicine Experimental Medicine, University of Oxford, Oxford, United Kingdom.

出版信息

J Allergy Clin Immunol. 2019 Sep;144(3):648-650. doi: 10.1016/j.jaci.2019.07.022. Epub 2019 Jul 31.

DOI:10.1016/j.jaci.2019.07.022
PMID:31376407
Abstract
摘要

相似文献

1
Is there a role for type 2 CD8 T cells in patients with steroid-resistant asthma?2型CD8 T细胞在激素抵抗性哮喘患者中起作用吗?
J Allergy Clin Immunol. 2019 Sep;144(3):648-650. doi: 10.1016/j.jaci.2019.07.022. Epub 2019 Jul 31.
2
[Cortisone-resistant bronchial asthma].
Ann Ital Med Int. 1996 Jul-Sep;11(3):187-95.
3
The other side of asthma: Steroid-refractory disease in the absence of TH2-mediated inflammation.哮喘的另一面:无TH2介导炎症情况下的激素难治性疾病。
J Allergy Clin Immunol. 2015 May;135(5):1196-8. doi: 10.1016/j.jaci.2015.01.032. Epub 2015 Mar 13.
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T cells and chronic asthma.
Int Arch Allergy Immunol. 1999 Feb-Apr;118(2-4):133-5. doi: 10.1159/000024049.
5
Sexual dimorphism: Is it relevant to steroid resistance or asthma control?
J Allergy Clin Immunol. 2009 Oct;124(4):688-90. doi: 10.1016/j.jaci.2009.08.029.
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CD8+ T cells in asthma: friend or foe?哮喘中的CD8 + T细胞:是友还是敌?
Pharmacol Ther. 2009 Feb;121(2):123-31. doi: 10.1016/j.pharmthera.2008.09.001. Epub 2008 Oct 1.
7
Expression of activation markers and cytokine mRNA by peripheral blood CD4 and CD8 T cells in atopic and nonatopic childhood asthma: effect of inhaled glucocorticoid therapy.特应性和非特应性儿童哮喘患者外周血CD4和CD8 T细胞活化标志物及细胞因子mRNA的表达:吸入糖皮质激素治疗的影响
Pediatrics. 2002 Feb;109(2):E24. doi: 10.1542/peds.109.2.e24.
8
Increased interleukin-4, interleukin-5, and interferon-gamma in airway CD4+ and CD8+ T cells in atopic asthma.特应性哮喘患者气道中CD4+和CD8+ T细胞白细胞介素-4、白细胞介素-5和干扰素-γ水平升高。
Am J Respir Crit Care Med. 2005 Feb 1;171(3):224-30. doi: 10.1164/rccm.200310-1416OC. Epub 2004 Oct 22.
9
Steroid-resistant asthma.激素抵抗性哮喘。
Paediatr Respir Rev. 2012 Sep;13(3):172-6; quiz 176-7. doi: 10.1016/j.prrv.2011.05.002.
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Interferon-gamma secretion of peripheral blood CD8+ T lymphocytes in patients with bronchial asthma: in vitro stimulus determines cytokine production.支气管哮喘患者外周血CD8 + T淋巴细胞的干扰素-γ分泌:体外刺激决定细胞因子产生。
Clin Exp Immunol. 2001 Nov;126(2):199-205. doi: 10.1046/j.1365-2249.2001.01666.x.

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Chronic Inflammation in Asthma: Looking Beyond the Th2 Cell.哮喘中的慢性炎症:超越辅助性T细胞2型的研究
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Integrative Roles of Pro-Inflammatory Cytokines on Airway Smooth Muscle Structure and Function in Asthma.促炎细胞因子在哮喘气道平滑肌结构和功能中的综合作用
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Type 2 immunity in allergic diseases.过敏性疾病中的2型免疫。
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CD8 T-cell subsets: heterogeneity, functions, and therapeutic potential.CD8 T 细胞亚群:异质性、功能和治疗潜力。
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Race/ethnicity-stratified fine-mapping of the MHC locus reveals genetic variants associated with late-onset asthma.按种族/族裔分层对MHC基因座进行精细定位,揭示了与迟发性哮喘相关的基因变异。
Front Genet. 2023 Jun 21;14:1173676. doi: 10.3389/fgene.2023.1173676. eCollection 2023.
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CD8 T cell differentiation status correlates with the feasibility of sustained unresponsiveness following oral immunotherapy.CD8 T 细胞分化状态与口服免疫治疗后持续无反应的可行性相关。
Nat Commun. 2022 Nov 4;13(1):6646. doi: 10.1038/s41467-022-34222-8.