Levi M I, Stepanova S L, Tunik A I, Livshits M M, Slizkova V G
Zh Mikrobiol Epidemiol Immunobiol. 1988 Apr(4):17-21.
The disinfecting effect of chloramine on P. aeruginosa depends on the concentration of this disinfecting agent, the concentration of P. aeruginosa and the period of exposure, with consideration for the time of attaining equilibrium between the concentration of chloramine and P. aeruginosa, affinity between the disinfectant and bacterial cells, the number of chloramine-binding sites on a bacterial cell, the admixture of organic substances, pH and other environmental characteristics. The interaction of chloramine and P. aeruginosa can be subdivided into two stages: (1) the binding of the disinfectant by bacterial cells and (2) the death of the microbes. The mathematical description of the process of disinfection requires that the main characteristics be expressed in molecular parameters and the time factor be correlated with the terms of attaining the equilibrium for free and bound chloramine. The average number of binding sites for chloramine on a bacterial cell and the affinity constant of chloramine to binding sites have been estimated.
氯胺对铜绿假单胞菌的消毒效果取决于该消毒剂的浓度、铜绿假单胞菌的浓度以及暴露时间，同时要考虑氯胺浓度与铜绿假单胞菌之间达到平衡的时间、消毒剂与细菌细胞之间的亲和力、细菌细胞上氯胺结合位点的数量、有机物质的混合、pH值及其他环境特征。氯胺与铜绿假单胞菌的相互作用可分为两个阶段：（1）细菌细胞对消毒剂的结合；（2）微生物的死亡。消毒过程的数学描述要求主要特征用分子参数表示，并且时间因素要与游离氯胺和结合氯胺达到平衡的条件相关联。已估算出细菌细胞上氯胺结合位点的平均数量以及氯胺与结合位点的亲和常数。
