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用麦卢卡蜂蜜敷料治疗导致阴茎完全剥脱的良性肿瘤:一例病例报告及文献综述

Benign tumours leading to total penile denudation treated with Manuka honey dressings: A case report and review of literature.

作者信息

Sylvester-Hvid Amalie, Avnstorp Magnus B, Fjeld Tobias, Crewe Bjørn

机构信息

Department of Plastic- and Breast Surgery, University Hospital Zealand, Sygehusvej 10, DK-4000, Roskilde, Denmark.

出版信息

Int J Surg Case Rep. 2019;61:191-194. doi: 10.1016/j.ijscr.2019.07.009. Epub 2019 Jul 19.

Abstract

INTRODUCTION

Penile denudation is a devastating condition often reconstructed with a split-thickness skin graft(STSG). As this kind of reconstruction is challenging, we present an non-invasive treatment using Manuka honey dressings with a satisfying result. This was performed as a salvage procedure after failed STSG.

CASE

A 55-year-old non-smoking male was admitted from his general practitioner with a newly onset of phimosis and lower urinary tract symptoms. Benign tumours complicated with infection were found on all segments of the penis causing dehiscence of the skin. After surgical removal of tumours and an unsuccessful STSG, Manuka honey dressings was used. Full sexual function was regained, and the patient was satisfied with the result.

DISCUSSION

Alternatives to STSG are full-thickness skin graft using the inguinal or scrotal borrowing method, or using a dermal matrix before a STSG. A rediscovered method is using Manuka honey, with its unique combination of bactericidal, anti-inflammatory and healing-promoting properties. A wide range of wound types may benefit from Manuka honey dressings. A recent Danish in vitro study on honey derived from various Danish floras even shows high antibacterial effect superior to commercial medical grade honey. Considering a growing resistance to antibiotics, medical honey may contribute as a alternative to extensive wound care.

CONCLUSION

We successfully treated a penile denudation with Manuka honey following a failed STSG. Wounds, ulcers, and burns may be infected, and can be challenging, time consuming, and expensive to treat. Manuka honey may be a good alternative to reconstructive surgery and can be managed on an out-patient basis.

摘要

引言

阴茎剥脱是一种严重的病症,通常采用中厚皮片移植(STSG)进行重建。由于这种重建具有挑战性,我们介绍一种使用麦卢卡蜂蜜敷料的非侵入性治疗方法,效果令人满意。这是在STSG失败后作为挽救性手术进行的。

病例

一名55岁不吸烟男性由全科医生转诊入院,患有新发包茎和下尿路症状。阴茎各段均发现良性肿瘤合并感染,导致皮肤裂开。手术切除肿瘤后STSG失败,遂使用麦卢卡蜂蜜敷料。患者恢复了完全性功能,对结果满意。

讨论

STSG的替代方法包括采用腹股沟或阴囊借用法的全厚皮片移植,或在STSG前使用真皮基质。一种重新发现的方法是使用麦卢卡蜂蜜,它具有杀菌、抗炎和促进愈合的独特组合特性。多种伤口类型可能受益于麦卢卡蜂蜜敷料。丹麦最近一项关于源自丹麦各种植物的蜂蜜的体外研究甚至表明,其抗菌效果优于商业医用级蜂蜜。考虑到对抗生素的耐药性不断增加,医用蜂蜜可能作为广泛伤口护理的一种替代方法。

结论

我们在STSG失败后用麦卢卡蜂蜜成功治疗了一例阴茎剥脱。伤口、溃疡和烧伤可能会感染,治疗起来可能具有挑战性、耗时且昂贵。麦卢卡蜂蜜可能是重建手术的一个很好的替代方法,并且可以在门诊进行处理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b976/6677685/6b338d64cff3/gr1.jpg

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