Francia I, Hernádi Z, Szabolcs M, Hernádi F
Central Research Laboratory, László Hospital, Budapest, Hungary.
Acta Biochim Biophys Hung. 1988;23(1):103-9.
The 60Co gamma-resistance inducing effect of R46 factor, and its elimination by 5-fluorouracil were studied. R46 increased the survival of the wild-type strain and its rec- mutants. After treatment with 5-fluorouracil (1 g/liter) the clones lost not only antibiotic resistance, but the 60Co gamma-radioresistance as well, encoded by R46 R-factor.