Francia I, Hernádi Z, Szabolcs M, Hernádi F
Central Research Laboratory, László Hospital, Budapest, Hungary.
Acta Biochim Biophys Hung. 1988;23(1):103-9.
The 60Co gamma-resistance inducing effect of R46 factor, and its elimination by 5-fluorouracil were studied. R46 increased the survival of the wild-type strain and its rec- mutants. After treatment with 5-fluorouracil (1 g/liter) the clones lost not only antibiotic resistance, but the 60Co gamma-radioresistance as well, encoded by R46 R-factor.
研究了R46因子诱导60Coγ抗性的作用及其被5-氟尿嘧啶消除的情况。R46提高了野生型菌株及其rec-突变体的存活率。用5-氟尿嘧啶（1克/升）处理后，这些克隆不仅失去了抗生素抗性，还失去了由R46 R因子编码的60Coγ辐射抗性。
