Endoscopy Unit, Alfa Institute of Gastroenterology, Clinics Hospital, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Instituto Alfa de Gatroenterologia, Universidade Federal de Minas Gerais - Medicine, Avenida Professor Alfredo Balena, 110, Santa Efigenia, Belo Horizonte, Minas Gerais, 30130-100, Brazil.
Obes Surg. 2020 Jan;30(1):238-243. doi: 10.1007/s11695-019-04120-y.
Esophagogastroduodenoscopy is a preoperative examination commonly required for candidates to bariatric surgery (BS). Overweight individuals have a greater risk of cardiorespiratory complications during endoscopy under sedation. This study aimed to investigate the feasibility, tolerance, and cardiovascular stress of transnasal endoscopy (TNE) without sedation in obese patients eligible for BS.
This prospective study enrolled obese adult patients with indication for BS that consented to undergo unsedated preoperative TNE. All examinations were carried out in an outpatient center. The outcomes assessed were endoscopic findings, procedural success, patients' tolerance according to a visual analogic scale, cardiovascular stress estimated by double product (i.e., systolic blood pressure × heart rate) and adverse events. Statistical analyses were used to compare each patient's double product among different examination periods.
Ninety-four patients (77.6% female) completed the study, with an average body mass index (BMI) of 53 kg/m (range, 35-73.4 kg/m). There were 63 super-obese individuals (67%), with BMI > 50 kg/m. In 93 patients (98.9%), unsedated TNE was successfully completed up to the second part of the duodenum. TNE failed in one patient. Tolerance was rated as excellent or good in 95.7%. Minimal cardiovascular stress was noted in obese individuals, whereas the double product remained stable throughout the procedure in super-obese patients. Three patients (3.2%) had self-limited epistaxis.
Unsedated TNE for preoperative endoscopic evaluation of obese patients is feasible, safe, and well tolerated and should be preferentially considered when examining super-obese patients.
食管胃十二指肠镜检查是肥胖症手术(BS)前常规检查。超重患者在镇静下接受内镜检查时,心肺并发症风险增加。本研究旨在探讨无镇静经鼻内镜(TNE)检查在符合 BS 条件的肥胖患者中的可行性、耐受性和心血管应激。
本前瞻性研究纳入了同意接受无镇静术前 TNE 的肥胖成年 BS 候选患者。所有检查均在门诊中心进行。评估的结果是内镜检查结果、手术成功率、患者根据视觉模拟量表的耐受性、双乘积(即收缩压×心率)估计的心血管应激和不良事件。使用统计学分析比较了不同检查期间每位患者的双乘积。
94 例患者(77.6%为女性)完成了研究,平均体重指数(BMI)为 53kg/m(范围,35-73.4kg/m)。有 63 例超肥胖患者(67%),BMI>50kg/m。93 例(98.9%)患者在未镇静的情况下成功完成了 TNE 检查至十二指肠第二部。1 例患者 TNE 失败。95.7%的患者耐受性评为极好或良好。肥胖患者的心血管应激极小,而超肥胖患者的双乘积在整个手术过程中保持稳定。3 例患者(3.2%)出现自限性鼻出血。
对于肥胖患者的术前内镜评估,无镇静 TNE 是可行、安全且耐受良好的,在检查超肥胖患者时应优先考虑。