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[替加氟、5-氟尿嘧啶和丝裂霉素C联合治疗不可切除胃癌的完全缓解病例]

[Complete response in a case of unresectable gastric cancer with a combination of tegafur, 5-fluorouracil and mitomycin C].

作者信息

Sasaki Y, Sasaki J, Ito T, Nehashi Y

机构信息

Dept. of Radiology, Chiba Cancer Center.

出版信息

Gan To Kagaku Ryoho. 1988 Sep;15(9):2793-5.

PMID:3137891
Abstract

A 75-year-old man with gastric cancer metastatic to the liver was treated by combined administration of Tegafur (800 mg/body/day), 5-fluorouracil (300 mg/body/day) and Mitomycin C (hepatic arterial infusion of 20 mg/body and intravenous infusion of 8 mg/body). The total dose of Tegafur was 5.6 g, that of 5-FU was 11.4 g, and that of MMC was 36 mg for one month and a half. After therapy, primary and metastatic sites was completely disappeared. The patient has survived for 6 years 8 months in a state of complete response.

摘要

一名75岁的男性,患有胃癌肝转移,接受替加氟(800毫克/体/天)、5-氟尿嘧啶(300毫克/体/天)和丝裂霉素C(肝动脉灌注20毫克/体,静脉输注8毫克/体)联合给药治疗。替加氟的总剂量为5.6克,5-氟尿嘧啶为11.4克,丝裂霉素C为36毫克,治疗持续一个半月。治疗后,原发灶和转移灶完全消失。患者在完全缓解状态下存活了6年8个月。

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