Coulibaly M, Toure M K, Koita S A, Coulibaly B B, Diop T M, Mangane M I, Al Meimoune A H, Nientao O, Dabo A, Diallo B, Dicko H, Konate M, Diango D M, Coulibaly Y
Service d'anesthésie-réanimation, CHU « Le Luxembourg », Bamako, Mali.
Département d'anesthésie-réanimation-médecine d'urgence, CHU Gabriel-Touré, Bamako, Mali.
Med Sante Trop. 2019 May 1;29(2):170-174. doi: 10.1684/mst.2019.0893.
The severity of a blood pressure spike is more closely associated with serious organ dysfunction, which can be life-threatening in the short term, than with the blood pressure level itself. A hypertensive emergency is defined as the presence of high blood pressure associated with acute organ dysfunction. The specific nature of high blood pressure in black patients may cause more frequent hypertensive emergencies. In this retrospective case study, we report our experience and highlight the specific prognosis for black African patients. We examined three patients, aged 27, 47, and 59 years, admitted to intensive care for a hypertensive emergency with neurological distress, and all in status epilepticus. Average blood pressure was 171 mm HG. Treatment included intubation, ventilation, and induction of a barbiturate coma, plus antihypertensive treatment. The outcome was favorable, with an average stay of 5 days. The frequency of hypertensive emergencies varies according to age, ethnic origin, and period studied. Black patients often suffer from more severe forms of high blood pressure, arising at an earlier age. Hypertensive encephalopathy can occur in patients with or without chronic hypertension. Without treatment, the encephalopathy induces a coma that can quickly become fatal. Its spontaneous course is catastrophic (10-20% survival at one year), but more favorable with adequate treatment (60-80% survival at five years).
血压骤升的严重程度与严重器官功能障碍的关联更为密切,严重器官功能障碍在短期内可能危及生命,而与血压水平本身的关联则较弱。高血压急症的定义为伴有急性器官功能障碍的高血压。黑人患者高血压的特殊性质可能导致更频繁的高血压急症。在这项回顾性病例研究中,我们报告了我们的经验,并强调了非洲黑人患者的具体预后情况。我们检查了三名年龄分别为27岁、47岁和59岁的患者,他们因伴有神经功能障碍的高血压急症入住重症监护病房,且均处于癫痫持续状态。平均血压为171毫米汞柱。治疗措施包括插管、通气、诱导巴比妥类药物昏迷以及降压治疗。结果良好,平均住院时间为5天。高血压急症的发生率因年龄、种族和所研究的时期而异。黑人患者常患更严重形式的高血压,且发病年龄较早。高血压脑病可发生于有或无慢性高血压的患者。未经治疗,脑病会导致昏迷,且可能迅速致命。其自发病程具有灾难性(一年生存率为10%-20%),但经过适当治疗则预后较好(五年生存率为60%-80%)。