Mapoure Njankouo Y, Mondomobe Atchom C, Halle M P, Mbatchou Ngahane B H, Luma N H
Faculté de médecine et des sciences pharmaceutiques, Université de Douala, Douala, Cameroun.
Med Sante Trop. 2019 May 1;29(2):184-189. doi: 10.1684/mst.2019.0895.
To determine the prevalence of HIV infection among stroke patients admitted to the Douala General Hospital (DGH) and to describe the clinical characteristics and outcome of the stroke patients with HIV infection. This prospective cohort study took place in 2010-2015 at the DGH. The study included patients older than 15 years with a CT-confirmed stroke. All patients underwent HIV tests with Western-Blot confirmation. The functional prognosis of the patients was assessed by the Rankin score at 6 months after stroke onset. The prevalence rate of HIV among stroke patients was 6.6% (40/608). Of the 40 HIV-positive patients, 58% were aware of their status at admission; 83% of these patients were receiving antiretroviral therapy. Males were predominant (65%), and the mean age was 51.3 ± 10.4 years. Hypertension was the main cerebrovascular risk factor (65%). At admission, 47.5% of HIV+ patients were febrile, and 7.5% presented with coma. Ischemic stroke accounted for 60% of cases. The mean CD4 cell count was 351 ± 236/mm with a median of 330/mm. The length of stay was 10 ± 8 days. At 6 months, the cumulative mortality of HIV+ patients was 37.5%, and 38.5% were dependent (Rankin>2). HIV prevalence is high among stroke patients in our setting. This suggests that an HIV test should be routinely proposed to stroke patients.
确定杜阿拉总医院（DGH）收治的中风患者中艾滋病毒感染的患病率，并描述艾滋病毒感染中风患者的临床特征和预后。这项前瞻性队列研究于2010年至2015年在DGH进行。该研究纳入了年龄大于15岁且CT确诊为中风的患者。所有患者均接受了艾滋病毒检测并经免疫印迹法确认。在中风发作后6个月，通过Rankin评分评估患者的功能预后。中风患者中艾滋病毒的患病率为6.6%（40/608）。在40名艾滋病毒阳性患者中，58%在入院时知晓自己的病情；其中83%的患者正在接受抗逆转录病毒治疗。男性占主导（65%），平均年龄为51.3±10.4岁。高血压是主要的脑血管危险因素（65%）。入院时，47.5%的艾滋病毒阳性患者发热，7.5%的患者出现昏迷。缺血性中风占病例的60%。平均CD4细胞计数为351±
