Chen Yixiao, Fang Xiaoyan, Shuai Xueqian, Fritzsche Kurt, Leonhart Rainer, Hoschar Sophia, Li Li, Ladwig Karl-Heinz, Ma Wenlin, Wu Heng
Department of Psychosomatic Medicine, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Institute of Epidemiology II, Mental Health Research Unit, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany.
Front Psychiatry. 2019 Jul 18;10:493. doi: 10.3389/fpsyt.2019.00493. eCollection 2019.
It is highly recommended that all patients with coronary artery disease should be screened for depression. The Major Depression Inventory (MDI) is a widely used self-rating scale for the assessment of depression but is not valid in Chinese language. The present study was designed to assess the reliability and validity of a version of the MDI translated into Chinese among patients with acute myocardial infarction (AMI). Data were derived from the "Multicenter Delay in Patients Experiencing Acute Myocardial Infarction in Shanghai" (MEDEA FAR-EAST) study. Using a cross-sectional study design, the Chinese version of the MDI was administered to a total of 267 inpatients. The internal consistency reliability of the MDI scale was evaluated based on the Cronbach's coefficient and the binary coefficient for the whole scale. Exploratory factor analysis was performed to assess the internal consistency of the MDI. To examine discriminant validity, we analyzed the correlation of the MDI score with the General Anxiety Disorder-7 (GAD-7) and World Health Organization-5 Well-Being Index (WHO-5) scale scores. The Chinese version of the MDI showed high reliability (Cronbach's alpha = 0.909, split-half reliability = 0.866). We identified one factor that explained 52% of the variance, which indicated that the MDI has satisfactory structural validity. The correlations of the MDI scores with the GAD-7 scores ( = 0.425) and the WHO-5 scores ( = -0.365) were moderate, suggesting that the MDI has acceptable discriminant validity. The MDI was proved to be a highly reliable and satisfactory valid diagnostic screening tool to assess depression in Chinese cardiac patients.
强烈建议对所有冠心病患者进行抑郁症筛查。重度抑郁量表（MDI）是一种广泛用于评估抑郁症的自评量表，但在中文环境中无效。本研究旨在评估翻译成中文的MDI版本在急性心肌梗死（AMI）患者中的信度和效度。数据来源于“上海急性心肌梗死患者多中心延迟”（MEDEA FAR-EAST）研究。采用横断面研究设计，对总共267名住院患者进行了中文版MDI测试。基于克朗巴赫系数和整个量表的二分系数评估MDI量表的内部一致性信度。进行探索性因子分析以评估MDI的内部一致性。为检验区分效度，我们分析了MDI得分与广泛性焦虑障碍-7（GAD-7）和世界卫生组织-5幸福指数（WHO-5）量表得分的相关性。中文版MDI显示出高信度（克朗巴赫α系数 = 0.909，分半信度 = 0.866）。我们识别出一个解释了52%变异的因子，这表明MDI具有令人满意的结构效度。MDI得分与GAD-7得分（= 0.425）和WHO-5得分（= -0.365）的相关性为中等，表明MDI具有可接受的区分效度。MDI被证明是一种高度可靠且令人满意的有效诊断筛查工具，用于评估中国心脏病患者的抑郁症。
