Robertson J N, Hogston P, Ward M E
University Department of Microbiology, Southampton General Hospital.
Br J Obstet Gynaecol. 1988 Jul;95(7):711-6. doi: 10.1111/j.1471-0528.1988.tb06535.x.
Sera from 50 women with ectopic pregnancy and 50 age-matched control women with intrauterine pregnancy were tested by enzyme-linked immunosorbent assay (ELISA) using C. trachomatis and N. gonorrhoeae pili as antigens. In the ectopic pregnancy group 76% had IgG antibodies to C. trachomatis compared with 38% in the controls. The prevalence of gonococcal IgG antibody was 32% in the ectopic pregnancy group and 4% in the controls. The prevalences of IgA antibodies to the two organisms ranged from 2 to 12% and were similar in the two groups; cultures for C. trachomatis from cervical swabs from the ectopic pregnancy group were negative. Chlamydial antigen was detected (by ELISA) in exfoliated cervical cells of only one patient in this group.
采用沙眼衣原体和淋病奈瑟菌菌毛作为抗原，通过酶联免疫吸附测定（ELISA）对50例异位妊娠女性及50例年龄匹配的宫内妊娠对照女性的血清进行检测。异位妊娠组中，76%的女性有沙眼衣原体IgG抗体，而对照组这一比例为38%。淋病奈瑟菌IgG抗体的患病率在异位妊娠组为32%，在对照组为4%。两组中针对这两种病原体的IgA抗体患病率在2%至12%之间，且两组相似；异位妊娠组宫颈拭子沙眼衣原体培养均为阴性。该组仅1例患者的脱落宫颈细胞中检测到（通过ELISA）衣原体抗原。
