环氧化酶和脂氧合酶抑制剂的抗氧化能力。
Antioxidant capacity of cyclo-oxygenase and lipoxygenase inhibitors.
作者信息
Felzenszwalb I, Asad N R, Alcantara-Gomes R
机构信息
Departamento de Ciências Fisiológicas, Universidade do Estado do Rio de Janeiro, Brasil.
出版信息
Braz J Med Biol Res. 1987;20(6):877-81.
PMID:3137994
Abstract
The present study analyzes the possible scavenger capacity of several anti-inflammatory drugs on growth of Escherichia coli K12, BW9 109, a strain hypersensitive to H2O2, in medium containing H2O2. Although all cyclo-oxygenase and/or lipoxygenase inhibitors protected the cells against H2O2, no correlation was found between their relative protective abilities and reported anti-inflammatory potencies.
摘要
本研究分析了几种抗炎药物在含有过氧化氢的培养基中对大肠杆菌K12（BW9 109，一种对过氧化氢高度敏感的菌株）生长的潜在清除能力。尽管所有环氧化酶和/或脂氧合酶抑制剂都能保护细胞免受过氧化氢的损伤，但未发现它们的相对保护能力与报道的抗炎效力之间存在相关性。
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