Ebrahimzadeh Attari Vahideh, Somi Mohammad Hosein, Asghari Jafarabadi Mohammad, Ostadrahimi Alireza, Moaddab Seyed-Yaghob, Lotfi Neda
Maragheh University of Medical Sciences, Maragheh, Iran.
Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Adv Pharm Bull. 2019 Jun;9(2):321-324. doi: 10.15171/apb.2019.038. Epub 2019 Jun 1.
The present study aimed to assess the effect of ginger (Zingiber officinale) powder supplementation on eradication and improvement of dyspeptic symptoms in patients with positive functional dyspepsia (FD). During this pilot study 15 patients with positive FD received 3 g/d ginger powder as three 1-g tablets for 4-weeks. Dyspepsia symptoms were asked before and after the intervention using a questionnaire based on the Rome III criteria. eradication was also assessed by a non-invasive stool antigen (HpSAg) test. Ginger consumption accompanied by significant eradication rate of 53.3% (P = 0.019) and the odds ratio (95% CI) was 8 (1.07 to 357.14). Moreover, our results showed significant changes in most of the dyspepsia symptoms after ginger supplementation. According to our findings, Z. officinale can be considered as a useful complementary therapy for FD. However, due to the small number of clinical trials in this area, further welldesigned clinical trials are needed to explicitly talk about its effectiveness especially about the eradication of .
本研究旨在评估补充姜粉对功能性消化不良（FD）阳性患者消化不良症状的根除及改善效果。在这项初步研究中，15例FD阳性患者每天服用3克姜粉，分3片1克的片剂，持续4周。使用基于罗马III标准的问卷在干预前后询问消化不良症状。还通过非侵入性粪便抗原（HpSAg）测试评估根除情况。食用姜伴随着53.3%的显著根除率（P = 0.019），优势比（95%CI）为8（1.07至357.14）。此外，我们的结果显示补充姜后大多数消化不良症状有显著变化。根据我们的研究结果，姜可被视为FD的一种有用的辅助疗法。然而，由于该领域的临床试验数量较少，需要进一步设计良好的临床试验来明确其有效性，特别是关于根除方面。
