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开放小关节去神经术作为腰椎管狭窄症后路减压患者的辅助治疗——一项单盲随机对照试验

Open facet joint denervation as an adjunct in patients undergoing posterior lumbar decompression for spinal stenosis-a single blinded randomized controlled trial.

作者信息

Faqeeh Ali, Yen David

机构信息

Kingston Health Sciences Centre and Queen's University, Kingston, ON, Canada.

出版信息

J Spine Surg. 2019 Jun;5(2):259-265. doi: 10.21037/jss.2019.05.06.

DOI:10.21037/jss.2019.05.06
PMID:31380480
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6626737/
Abstract

BACKGROUND

Facet radiofrequency denervation is a prevalent procedure used to try and relieve back pain. Despite the increasing use of this treatment, its effectiveness has been questioned. In consideration of the conflicting reports in the literature, we sought to conduct a trial to study the short-term effect of facet denervation in patients undergoing lumbar laminectomy(s) to determine the short-term effect of adding facet denervation to patients undergoing lumbar laminectomy(s) where the anatomy was exposed, allowing an open technique to be used for the denervation.

METHODS

Sixty patients with a diagnosis of degenerative lumbar spinal stenosis who complained of neurogenic claudication and back pain for at least 3 months were randomized to undergo a lumbar laminectomy(s) either with or without facet joint denervation. Pain and self-reported function using a 10 cm visual analogue scale (VAS) and the Roland-Morris Disability Questionnaire (RMDQ) were measured before surgery and at patients' 6-, 12- and 24-week follow-up clinic visit. Various parametric and non-parametric tests including the Chi-square, independent samples -tests, the Mann Whitney U, Wilcoxon sign ranks, one-way ANOVA with a Bonferroni test were used to analyze the data. The RMDQ scores were analyzed between groups and within groups over time.

RESULTS

No differences in pain or functional ability were seen between groups. Both groups significantly improved in both pain and function from baseline to follow up times.

CONCLUSIONS

Our findings do not support the addition of facet denervation for short-term treatment of back pain in patients undergoing lumbar laminectomy(s) for spinal stenosis within our study design.

摘要

背景

小关节射频去神经术是一种常用于尝试缓解背痛的普遍手术。尽管这种治疗方法的使用越来越多,但其有效性一直受到质疑。鉴于文献中的报道相互矛盾,我们试图进行一项试验,以研究小关节去神经术对接受腰椎椎板切除术患者的短期效果,以确定在解剖结构暴露、允许采用开放技术进行去神经术的情况下,对接受腰椎椎板切除术的患者增加小关节去神经术的短期效果。

方法

60例诊断为退变性腰椎管狭窄症、主诉神经源性间歇性跛行和背痛至少3个月的患者被随机分为接受或不接受小关节去神经术的腰椎椎板切除术组。在手术前以及患者术后6周、12周和24周的随访门诊中,使用10厘米视觉模拟量表(VAS)和罗兰-莫里斯残疾问卷(RMDQ)测量疼痛和自我报告的功能。使用各种参数和非参数检验,包括卡方检验、独立样本t检验、曼-惠特尼U检验、威尔科克森符号秩检验、带有邦费罗尼检验的单因素方差分析来分析数据。随时间对组间和组内的RMDQ评分进行分析。

结果

两组在疼痛或功能能力方面均未观察到差异。从基线到随访期,两组在疼痛和功能方面均有显著改善。

结论

在我们的研究设计中,我们的研究结果不支持对因椎管狭窄接受腰椎椎板切除术的患者增加小关节去神经术用于短期治疗背痛。

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本文引用的文献

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Effect of Radiofrequency Denervation on Pain Intensity Among Patients With Chronic Low Back Pain: The Mint Randomized Clinical Trials.射频去神经术对慢性下腰痛患者疼痛强度的影响:薄荷随机临床试验
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Percutaneous lumbar zygapophysial (Facet) joint neurotomy using radiofrequency current, in the management of chronic low back pain: a randomized double-blind trial.使用射频电流进行经皮腰椎小关节神经切断术治疗慢性下腰痛:一项随机双盲试验
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A comparison of conventional and pulsed radiofrequency denervation in the treatment of chronic facet joint pain.传统与脉冲射频去神经术治疗慢性小关节疼痛的比较
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Effectiveness of repeated radiofrequency neurotomy for lumbar facet pain.重复射频神经切断术治疗腰椎小关节疼痛的疗效
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Radiofrequency facet joint denervation in the treatment of low back pain: a placebo-controlled clinical trial to assess efficacy.射频小关节去神经术治疗腰痛:一项评估疗效的安慰剂对照临床试验
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