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患有注意力缺陷多动障碍(ADHD)的老年人的生活质量:与ADHD症状水平和执行功能缺陷的关联。

Quality of life in older adults with ADHD: links to ADHD symptom levels and executive functioning deficits.

作者信息

Thorell Lisa B, Holst Ylva, Sjöwall Douglas

机构信息

Department of Clinical Neuroscience, Karolinska Institutet , Stockholm , Sweden.

Habilitation and Health, Stockholm County Council , Stockholm , Sweden.

出版信息

Nord J Psychiatry. 2019 Oct;73(7):409-416. doi: 10.1080/08039488.2019.1646804. Epub 2019 Aug 5.

Abstract

The overall aim of the present study was to examine quality of life in attention deficit hyperactivity disorder (ADHD) patients age ≥60 years. First, we compared older adults with ADHD to both healthy controls of the same age and younger adults with ADHD. Second, we examined executive functioning as a possible underlying factor for quality of life among older adults with ADHD. The study included 158 participants in three groups: (1) older adults (60-75 years of age) with ADHD ( = 42), (2) healthy controls of the same age ( = 58), and (3) younger adults (age 18-45 years of age) with ADHD ( = 56). The patients with ADHD were clinically-referred. Quality of life was examined through self-ratings and executive functioning was examined using both self-ratings and tests. Older adults with ADHD differed significantly from controls the same age on all aspects of quality of life, with large effect sizes. However, they showed similar levels of quality of life compared to younger adults with ADHD. The exception was psychological health, for which older adults displayed better quality of life compared to younger adults with ADHD. Executive deficits measured through self-ratings, especially working memory, were related to quality of life, sometimes also beyond the influence of ADHD symptom levels. Older adults with ADHD show serious impairments in quality of life, that are comparable to the levels found for younger adults. Impairments may increase further as these individuals grow older and clinics need to meet the needs of this increasingly larger group of patients.

摘要

本研究的总体目标是调查年龄≥60岁的注意力缺陷多动障碍(ADHD)患者的生活质量。首先,我们将患有ADHD的老年人与同龄健康对照组以及患有ADHD的年轻成年人进行了比较。其次,我们研究了执行功能作为患有ADHD的老年人生活质量的一个可能潜在因素。该研究纳入了158名参与者,分为三组:(1)患有ADHD的老年人(60 - 75岁)(n = 42),(2)同龄健康对照组(n = 58),以及(3)患有ADHD的年轻成年人(18 - 45岁)(n = 56)。患有ADHD的患者是临床转诊而来的。通过自我评分来检查生活质量,并使用自我评分和测试来检查执行功能。患有ADHD的老年人在生活质量的各个方面与同龄对照组相比有显著差异,效应量较大。然而,与患有ADHD的年轻成年人相比,他们的生活质量水平相似。心理健康方面是个例外,患有ADHD的老年人在心理健康方面的生活质量比年轻成年人更好。通过自我评分测量的执行缺陷,尤其是工作记忆,与生活质量相关,有时这种相关性还超出了ADHD症状水平的影响。患有ADHD的老年人在生活质量方面存在严重损害,与年轻成年人的损害水平相当。随着这些个体年龄的增长,损害可能会进一步加剧,临床机构需要满足这一越来越庞大的患者群体的需求。

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