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推荐定义在识别青少年高血压中的验证。

Validation of recommended definition in identifying elevated blood pressure in adolescents.

机构信息

Department of Preventive Medicine, North Sichuan Medical College, Nanchong, China.

Applied biostatistics laboratory, University of Michigan School of Nursing, Ann Arbor, MI, USA.

出版信息

J Clin Hypertens (Greenwich). 2019 Sep;21(9):1343-1349. doi: 10.1111/jch.13640. Epub 2019 Aug 5.

Abstract

Recently, the American Academy of Pediatrics (AAP) recommended 120/80 mm Hg as thresholds for identifying elevated blood pressure (BP) in adolescents aged 13-17 years. The authors aimed to compare the performance of the new definition in identifying elevated BP with traditional percentile-based definition. Data were obtained from the National Health and Nutrition Examination Survey 1999-2014, which included 7485 adolescents aged 13-17 years. Elevated BP was defined using the recommended (≥120/80 mm Hg) and traditional definition (≥90th percentile for sex, age, and height or 120/80 mm Hg) presented in AAP guideline. The prevalence of elevated BP was 15.7% and 17.2% using the recommended and traditional definition, respectively (P < .001). The recommended definition had high sensitivity (90.9%), perfect specificity (100.0%), perfect positive predictive value (100.0%), and very high negative predictive value (98.1%) compared with the traditional definition. The Kappa correlation coefficient between two definitions was 0.94 (P < .001). Similar results can be observed in subgroups across sex, age, and sex- and age-specific height percentile except for both sexes with young age and low height percentile. Generally, our results supported the use of the recommended definition for identifying elevated BP in adolescents.

摘要

最近,美国儿科学会(AAP)建议将 120/80mmHg 作为 13-17 岁青少年血压升高的阈值。作者旨在比较新定义与传统基于百分位的定义在识别高血压方面的表现。数据来自 1999-2014 年的全国健康和营养调查,包括 7485 名 13-17 岁的青少年。高血压的定义采用 AAP 指南中推荐的(≥120/80mmHg)和传统定义(性别、年龄和身高的第 90 百分位或 120/80mmHg)。使用推荐和传统定义,高血压的患病率分别为 15.7%和 17.2%(P<0.001)。与传统定义相比,推荐的定义具有较高的敏感性(90.9%)、完美的特异性(100.0%)、完美的阳性预测值(100.0%)和非常高的阴性预测值(98.1%)。两种定义之间的 Kappa 相关系数为 0.94(P<0.001)。除了男女均处于低年龄和低身高百分位的情况外,在性别、年龄和性别及年龄特定身高百分位的亚组中均可观察到相似的结果。一般来说,我们的结果支持使用推荐的定义来识别青少年的高血压。

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