Heymer B, Wirsing von König C H, Finger H, Hof H, Emmerling P
Department of Pathology, University of Ulm.
Infection. 1988;16 Suppl 2:S106-11. doi: 10.1007/BF01639731.
This paper is a survey of the histomorphology of experimental listeriosis based on cooperative studies performed within the past ten years. The influence of various parameters of the infectious agent (pathogenic Listeria monocytogenes serovar 4b, nonpathogenic Listeria innocua serovar 6b etc.) as well as of the host (euthymic NMRI-mice conditioned with dextran sulfate 500 or cyclosporin A, athymic nude mice etc.) on the course, morphology and outcome of the Listeria infection was investigated. From the experimental models used and the studies performed much could be learned concerning the factors that determine the histomorphological manifestations of listeriosis in humans.
本文是基于过去十年内合作开展的研究，对实验性李斯特菌病组织形态学的一项综述。研究了感染因子的各种参数（致病性单核细胞增生李斯特菌血清型4b、无致病性无害李斯特菌血清型6b等）以及宿主（用硫酸葡聚糖500或环孢素A预处理的正常胸腺NMRI小鼠、无胸腺裸鼠等）对李斯特菌感染的病程、形态学及转归的影响。从所使用的实验模型及开展的研究中，可以了解到很多关于决定人类李斯特菌病组织形态学表现的因素。
