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舌原发性淋巴瘤致三叉神经痛 1 例报告

A case report of a primary lymphoma of the tongue presenting as trigeminal neuralgia.

机构信息

Division of Radiation Oncology, Department of Oncology, London Regional Cancer Program, 800 Commissioners Road East, London, Ontario, N6A 5W9, Canada.

Division of Hematology, Department of Medicine, London Regional Cancer Program, 800 Commissioners Road East, London, Ontario, N6A 5W9, Canada.

出版信息

J Otolaryngol Head Neck Surg. 2019 Aug 5;48(1):37. doi: 10.1186/s40463-019-0360-9.

DOI:10.1186/s40463-019-0360-9
PMID:31383004
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6683536/
Abstract

BACKGROUND

Primary lymphoma of the oral cavity is a rare phenomenon. Herein we describe a unique presentation of lymphoma of the tongue which initially manifested as trigeminal neuralgia.

CASE PRESENTATION

A 63-year-old female experienced a 10-month history of paresthesia and neuropathic pain involving the left tongue and mandibular area of her face. Investigations including imaging and biopsy revealed primary lymphoma of the tongue with extensive perineural spread. The patient underwent standard chemotherapy with complete radiological response, but minimal recovery of the affected neurological functions.

CONCLUSION

This case highlights an unusual presentation of a rare disease leading to a delay in diagnosis and the importance of a complete workup for trigeminal neuropathy.

摘要

背景

口腔原发性淋巴瘤是一种罕见的现象。在此,我们描述了一种舌部淋巴瘤的独特表现,其最初表现为三叉神经痛。

病例介绍

一名 63 岁女性患者出现了 10 个月的左舌部和下颌面部麻木和神经病理性疼痛。包括影像学和活检在内的检查显示,原发性舌部淋巴瘤广泛累及神经外膜。患者接受了标准的化疗,影像学完全缓解,但受累神经功能仅出现轻微恢复。

结论

该病例提示了一种罕见疾病的不常见表现,导致诊断延迟,强调了全面检查三叉神经病变的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acaa/6683536/715d10105902/40463_2019_360_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acaa/6683536/5b68d7156023/40463_2019_360_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acaa/6683536/715d10105902/40463_2019_360_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acaa/6683536/5b68d7156023/40463_2019_360_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acaa/6683536/715d10105902/40463_2019_360_Fig2_HTML.jpg

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Oral manifestations of lymphoma: a systematic review.淋巴瘤的口腔表现:一项系统评价。
Ecancermedicalscience. 2016 Aug 17;10:665. doi: 10.3332/ecancer.2016.665. eCollection 2016.
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Mechanisms of Perineural Invasion.神经周围浸润的机制。
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