Gonella Marie C, Fischbein Nancy J, So Yuen T
Department of Neurology, Stanford University Medical Center, Stanford, California, USA.
Semin Neurol. 2009 Feb;29(1):36-44. doi: 10.1055/s-0028-1124021. Epub 2009 Feb 12.
The management of patients with trigeminal system dysfunction requires an understanding of the system's complex anatomy, which extends from peripheral nerve endings, through the skull base, cavernous sinus (V1, V2 only), and trigeminal ganglion, to the intraaxial nuclei, tracts, and cerebral cortex. The differential diagnosis is broad. Seemingly minor facial sensory loss may indicate an underlying malignancy (as in numb-chin syndrome). Painful syndromes of the trigeminal nerve are numerous and require careful categorization. Understanding trigeminal system anatomy and the appropriate use of imaging and electrodiagnostics should aid in the diagnosis and treatment of these disorders.
三叉神经系统功能障碍患者的管理需要了解该系统复杂的解剖结构，其范围从周围神经末梢开始，穿过颅底、海绵窦（仅V1、V2）和三叉神经节，直至轴内神经核、神经束和大脑皮层。鉴别诊断范围广泛。看似轻微的面部感觉丧失可能提示潜在的恶性肿瘤（如麻木性下颌综合征）。三叉神经的疼痛综合征众多，需要仔细分类。了解三叉神经系统解剖结构以及正确使用影像学和电诊断方法应有助于这些疾病的诊断和治疗。
