Department of Surgery, Microbiome Center, University of Chicago, 5841 S. Maryland Street, Chicago, IL 60637, USA; Division of Academic Internal Medicine, Department of Medicine, Institute for Health Research and Policy Cancer Center, University of Illinois at Chicago, 1747 W. Roosevelt Road, Chicago, IL 60608, USA.
Division of Academic Internal Medicine, Department of Medicine, Institute for Health Research and Policy Cancer Center, University of Illinois at Chicago, 1747 W. Roosevelt Road, Chicago, IL 60608, USA.
Gastroenterol Clin North Am. 2019 Sep;48(3):433-445. doi: 10.1016/j.gtc.2019.04.007.
Perinatal mood and anxiety disorders (PMAD) have significant negative impacts on mother and child, yet treatments are limited. Adequate nutrition during the perinatal period is essential to maternal and infant health, including maternal mental health and the child's neurologic and neuropsychiatric development. Nutrition holds promise to improve prevention and treatment of PMAD. The ability to manipulate the gut microbiota composition and structure through host nutrition and to harness the gut microbes for improved individualized nutrition may be an important new direction for prevention and treatment of PMAD, thus improving the mental health of mother and child.
围产期情绪和焦虑障碍 (PMAD) 对母婴有重大负面影响,但治疗方法有限。围产期充足的营养对于母婴健康至关重要,包括产妇的心理健康以及儿童的神经和神经精神发育。营养有望改善 PMAD 的预防和治疗。通过宿主营养来操纵肠道微生物群落组成和结构,并利用肠道微生物来改善个体化营养,这可能是预防和治疗 PMAD 的一个重要新方向,从而改善母婴的心理健康。