Rivera César
Oral Medicine and Pathology Research Group, Department of Basic Biomedical Sciences, Faculty of Health Sciences, University of Talca, Talca, Maule 3460000, Chile.
Biomed Rep. 2019 Aug;11(2):47-50. doi: 10.3892/br.2019.1221. Epub 2019 Jun 11.
Recurrent aphthous stomatitis (RAS), also known as canker sores, is the most common disease of the oral mucosa. Unlike caries and periodontal disease, patients with RAS are unable to prevent it. The clinical picture of RAS is characterized by recurrent episodes of solitary or multiple painful ulcerations without association with systemic diseases. The objective of this review is to present the essential characteristics of RAS, including its definition, pathogenesis, clinical and microscopic characteristics, proposed experimental models and recommended pharmacological management. This understanding can serve as a theoretical framework for research proposals.
复发性阿弗他口炎(RAS),也称为口腔溃疡,是口腔黏膜最常见的疾病。与龋齿和牙周病不同,RAS患者无法预防该病。RAS的临床表现为反复发作的单个或多个疼痛性溃疡,且与全身性疾病无关。本综述的目的是介绍RAS的基本特征,包括其定义、发病机制、临床和微观特征、提出的实验模型以及推荐的药物治疗。这种认识可作为研究提案的理论框架。