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慢性酒精滥用与丙型肝炎病毒的自发清除

Chronic alcohol abuse and spontaneous clearance of hepatitis C virus.

作者信息

Pott Henrique, Bricks Guilherme, Senise Jorge Figueiredo, Castelo Adauto

机构信息

Departament of Medicine, Universidade Federal de São Carlos (UFSCar), São Carlos, Brazil.

Division of Infectious Diseases, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.

出版信息

IDCases. 2019 Apr 6;17:e00534. doi: 10.1016/j.idcr.2019.e00534. eCollection 2019.

Abstract

Spontaneous clearance of hepatitis C virus (HCV) is an uncommon occurrence in the course of chronic infection. We reported a rare case of a 41-year-old male patient infected with HCV genotype 3a who presented spontaneous viral elimination after increasing his daily consumption of alcoholic beverage. In this short review, we overview how modulation of the hepatic inflammatory response could have a role in the viral elimination process.

摘要

丙型肝炎病毒(HCV)的自发清除在慢性感染过程中并不常见。我们报告了一例罕见病例,一名41岁感染HCV 3a基因型的男性患者,在增加每日酒精饮料摄入量后出现了病毒的自发清除。在这篇简短的综述中,我们概述了肝脏炎症反应的调节如何在病毒清除过程中发挥作用。

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本文引用的文献

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Adaptive immune response during hepatitis C virus infection.丙型肝炎病毒感染期间的适应性免疫反应。
World J Gastroenterol. 2014 Apr 7;20(13):3418-30. doi: 10.3748/wjg.v20.i13.3418.

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