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[食管气管瘘和食管支气管瘘的外科治疗]

[Surgical treatment of esophagotracheal and esophagobronchial fistulas].

作者信息

Mann C, Musholt T J, Babic B, Hürtgen M, Gockel I, Thieringer F, Lang H, Grimminger P P

机构信息

Klinik für Allgemein‑, Viszeral- und Transplantationschirurgie, Universitätsmedizin der Johannes-Gutenberg-Universität Mainz, Langenbeckstr. 1, 55131, Mainz, Deutschland.

Klinik für Thoraxchirurgie, Katholisches Klinikum Koblenz-Montabaur, Koblenz, Deutschland.

出版信息

Chirurg. 2019 Sep;90(9):722-730. doi: 10.1007/s00104-019-1006-1.

Abstract

BACKGROUND

Esophagotracheal and esophagobronchial fistulas are pathological communications between the airway system and the digestive tract, which often lead to major pulmonary complications with a high mortality. Endoscopic treatment is the primary therapeutic approach; however, in cases of failure early surgical treatment is obligatory.

METHODS

This article describes the clinical course of patients with esophagotracheal and esophagobronchial fistulas treated in this hospital over a period of 10 years. Patients were retrospectively analyzed with respect to the etiology of fistulas, management, in particular to the operative procedures, complications and outcome.

RESULTS

Between 2009 and 2019, a total of 15 patients with esophagotracheal and esophagobronchial fistula were treated in this hospital. Of these 12 underwent an endoscopic intervention, of which 5 were successful. In total, eight patients needed surgical intervention, six of the eight surgically treated patients recovered fully, one had a recurrent fistula, which was successfully treated by subsequent endoscopy after surgery and one patient died.

DISCUSSION

Management of esophagotracheal and esophagobronchial fistulas is challenging. This retrospective analysis reflects the published data with a success rate of endoscopic treatment in approximately 50%. Surgical intervention should be carried out after unsuccessful endoscopic treatment or if endoscopic treatment is primarily not feasible. Direct closure with resorbable sutures or reconstruction with alloplastic or allogeneic material should be preferred. For larger defects or high proximal esophagotracheal fistulas local transposition of muscular flaps or free muscular flaps play a major role. During operative closure of high intrathoracic or cervical fistulas, intraoperative neuromonitoring can be useful to prevent nerve damage.

摘要

背景

食管气管瘘和食管支气管瘘是气道系统与消化道之间的病理性通道,常导致严重的肺部并发症,死亡率很高。内镜治疗是主要的治疗方法;然而,若治疗失败,则必须尽早进行手术治疗。

方法

本文描述了本院10年间收治的食管气管瘘和食管支气管瘘患者的临床病程。对患者的瘘管病因、治疗方法,尤其是手术操作、并发症及治疗结果进行了回顾性分析。

结果

2009年至2019年,本院共收治15例食管气管瘘和食管支气管瘘患者。其中12例接受了内镜干预,5例成功。总共有8例患者需要手术干预,8例接受手术治疗的患者中有6例完全康复,1例出现复发性瘘管,术后通过后续内镜检查成功治疗,1例患者死亡。

讨论

食管气管瘘和食管支气管瘘的治疗具有挑战性。这项回顾性分析反映了已发表的数据,内镜治疗的成功率约为50%。在内镜治疗失败或内镜治疗根本不可行时,应进行手术干预。应首选使用可吸收缝线直接缝合或用异体或同种异体材料进行重建。对于较大的缺损或高位近端食管气管瘘,局部肌瓣转移或游离肌瓣发挥主要作用。在手术闭合高位胸内或颈段瘘管时,术中神经监测有助于预防神经损伤。

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