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犬用磁压迫技术治疗气管食管瘘。

Tracheoesophageal fistula treated with magnetic compression technique in canines.

机构信息

Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, 710061, Shaanxi, China.

Department of Thoracic Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.

出版信息

Sci Rep. 2023 Mar 24;13(1):4830. doi: 10.1038/s41598-023-31903-2.

Abstract

There are various surgical methods for tracheoesophageal fistula; however, there is presently no unified standard. Based on the magnetic compression technique, we designed a novel method for the treatment of tracheoesophageal fistula. The purpose of this study was to verify its feasibility in an animal experiment. Six beagle dogs underwent surgical repair after constructing a tracheoesophageal fistula model. After the tracheal and esophageal spaces were freed during the operation, two magnets were used to clamp the fistula. The operation time, intraoperative blood loss, postoperative complications, and wound healing were monitored. Samples were obtained 14 days after the operation, and fistula repair was observed. The tracheoesophageal fistula repair operation was successfully completed for all six beagles. The average operation time was 23.67 ± 4.50 min. The average intraoperative blood loss was less than 10 mL. One dog had a postoperative wound infection, and the rest had no postoperative complications. The wound healed well. In all dogs, after specimen collection, it was observed that the fistula was successfully closed and the mucosal layer was smooth and flat. Histological observation showed that the anastomosis was slightly inflamed, the mucosal layer and surrounding tissues were arranged neatly, and the structure was slightly disordered. Magnetic compression technique can be effectively used to repair tracheoesophageal fistula, shorten the operation time, and simplify the operation procedure, and thus, it has the potential for clinical application.

摘要

治疗气管食管瘘有多种手术方法,但目前尚无统一标准。基于磁压迫技术,我们设计了一种治疗气管食管瘘的新方法。本研究旨在通过动物实验验证其可行性。

6 只比格犬在建立气管食管瘘模型后接受手术修复。手术中,在游离气管和食管间隙后,使用两个磁铁夹闭瘘口。监测手术时间、术中出血量、术后并发症和伤口愈合情况。术后 14 天取标本,观察瘘口修复情况。

所有 6 只比格犬均成功完成气管食管瘘修复手术。平均手术时间为 23.67±4.50 分钟。平均术中出血量小于 10 毫升。1 只狗术后伤口感染,其余无术后并发症。伤口愈合良好。所有狗在采集标本后,观察到瘘口成功闭合,黏膜层光滑平坦。组织学观察显示吻合口轻度炎症,黏膜层和周围组织排列整齐,结构略有紊乱。

磁压迫技术可有效用于修复气管食管瘘,缩短手术时间,简化手术步骤,具有临床应用潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ddb/10038985/8981eb40f252/41598_2023_31903_Fig1_HTML.jpg

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