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广泛自闭症表型症状在同胞中的筛查:对症状表现的一种独特模型的支持。

Screening of Broader Autism Phenotype Symptoms in Siblings: Support for a Distinct Model of Symptomatology.

机构信息

Department of Psychology, The University of Alabama, Box 870348, Tuscaloosa, AL, 35487, USA.

出版信息

J Autism Dev Disord. 2019 Nov;49(11):4686-4690. doi: 10.1007/s10803-019-04157-z.

Abstract

Research on siblings of youth with autism spectrum disorder (ASD) suggests that some phenotypic presentation, known as the broader autism phenotype (BAP), is common among siblings without an ASD diagnosis (e.g., Ruzich et al. in Autism Res 9(6):658-665, 2016). Whereas the symptoms that underlie both ASD and the BAP share commonality, the structure of these symptoms in youth with ASD and their siblings may differ. The current study assessed whether differences arise in the factor structure of the Children's Social Behavior Questionnaire (CSBQ) between youth with ASD and their siblings in a sample of 221 sibling dyads. Results suggest similar factor structures for ASD and BAP; however, number of symptoms endorsed, as opposed to the degree of severity, may better differentiate BAP.

摘要

对自闭症谱系障碍(ASD)青年的兄弟姐妹的研究表明,一些表型表现,称为广泛自闭症表型(BAP),在没有 ASD 诊断的兄弟姐妹中很常见(例如,Ruzich 等人,自闭症研究,9(6):658-665,2016)。虽然 ASD 和 BAP 所依据的症状具有共同性,但 ASD 儿童及其兄弟姐妹的这些症状的结构可能不同。本研究在 221 对兄弟姐妹样本中,评估了 ASD 儿童及其兄弟姐妹的儿童社交行为问卷(CSBQ)的因子结构是否存在差异。结果表明,ASD 和 BAP 的因子结构相似;然而,区分 BAP 的可能是症状的数量,而不是严重程度。

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