Poplack D G, Reaman G
Leukemia Biology Section, National Cancer Institute, Bethesda, Maryland.
Pediatr Clin North Am. 1988 Aug;35(4):903-32. doi: 10.1016/s0031-3955(16)36515-4.
This article reviews the current biologic understanding of acute lymphoblastic leukemia and describes current approaches to treatment. It discusses the areas likely to be the focus of future research for this disease, including therapy for high-risk patients, understanding the reasons for treatment failure, and identification of new antileukemic agents.
本文综述了目前对急性淋巴细胞白血病的生物学认识,并描述了当前的治疗方法。它讨论了可能成为该疾病未来研究重点的领域,包括高危患者的治疗、理解治疗失败的原因以及鉴定新的抗白血病药物。