Al-Hussaini Maysa, Ammar Khawlah, Kasasbeh Nour, Sultan Hala, Al-Omari Amal
Department of Pathology and Laboratory Medicine, King Hussein Cancer Center, Amman, Jordan.
Office of Human Research Protection Program (HRPP), King Hussein Cancer Center, Amman, Jordan.
J Genet Couns. 2019 Oct;28(5):1021-1028. doi: 10.1002/jgc4.1154. Epub 2019 Aug 6.
Celebrities' health decisions have long been associated with heightened awareness and health trend changes. This is the first study conducted in an Arab population investigating the impact of international celebrity news on local communities using the case of Angelia Jolie's (AJ) prophylactic mastectomy and oophorectomy surgeries. The objective was to measure the effect of publicized medical information on cancer genetic testing knowledge, attitudes, and practices (KAP). This is a cross-sectional study using a semi-structured, self-administered questionnaire for clinic visitors at the King Hussein Cancer Center (KHCC). We had predominantly female (n = 262, 66.3%) and healthy participants (n = 248, 66.5%). Approximately 80.7% (n = 330) recognized AJ, the actress, and of these, 71% (n = 232) were aware of her recent diagnosis and prophylactic surgeries. Males reported a higher knowledge score (p < .001). However, females had more initiative to seek information (18.3% vs. 10.1%; p = .04). People aware of Angelina's prophylactic procedures were inclined to seek information regarding cancer genetics (20.8% vs. 9.6% p = .003). Breast and ovarian cancer patients were more likely than other cancer patients to encourage family members to undergo prophylactic surgery in case of BRCA1/2 mutations (39.2% vs. 17.1% p = .03). Ninety-three percent of the sample lacked knowledge regarding the availability of cancer genetic testing in Jordan. Results highlight a clear effect of celebrity medical news on our population, as well as openness to consider genetic testing as an early detection tool for women with a family history of breast and/or ovarian cancer. Generalization of these results to the population of Jordan requires further studies.
名人的健康决策长期以来一直与更高的关注度和健康趋势变化相关联。这是在阿拉伯人群中进行的第一项研究，以安吉丽娜·朱莉（AJ）的预防性乳房切除术和卵巢切除术为例，调查国际名人新闻对当地社区的影响。目的是衡量公开的医疗信息对癌症基因检测知识、态度和实践（KAP）的影响。这是一项横断面研究，使用半结构化的自填问卷对侯赛因国王癌症中心（KHCC）的门诊患者进行调查。我们的参与者主要为女性（n = 262，66.3%）且健康（n = 248，66.5%）。约80.7%（n = 330）的人认识女演员AJ，其中71%（n = 232）知晓她最近的诊断和预防性手术。男性的知识得分更高（p <.001）。然而，女性更主动寻求信息（18.3%对10.1%；p =.04）。知晓安吉丽娜预防性手术的人倾向于寻求有关癌症遗传学的信息（20.8%对9.6%，p =.003）。乳腺癌和卵巢癌患者比其他癌症患者更有可能鼓励家庭成员在存在BRCA1/2突变的情况下接受预防性手术（39.2%对17.1%，p =.03）。93%的样本对约旦可进行癌症基因检测的情况缺乏了解。结果凸显了名人医疗新闻对我们人群的明显影响，以及人们愿意将基因检测视为有乳腺癌和/或卵巢癌家族史女性的早期检测工具。将这些结果推广到约旦人群需要进一步研究。
