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不同类型痴呆症患者的驾驶能力:最新研究进展。

Driving Fitness in Different Forms of Dementia: An Update.

机构信息

Evangelisches Klinikum Bethel, Research Division, Department of Psychiatry and Psychotherapy Bethel, Bielefeld, Germany.

Evangelisches Klinikum Bethel, Division of Geriatric Psychiatry, Department of Psychiatry and Psychotherapy Bethel, Bielefeld, Germany.

出版信息

J Am Geriatr Soc. 2019 Oct;67(10):2186-2192. doi: 10.1111/jgs.16077. Epub 2019 Aug 6.

Abstract

BACKGROUND/OBJECTIVES: Most forms of dementia are associated with progressive cognitive and noncognitive impairments that can severely affect fitness to drive. Whether safe driving is still possible in the single case, however, is often difficult to decide and may be dependent on both severity and type of the respective dementia syndrome. Particularly in early disease stages, Alzheimer disease dementia (ADD) and different types of non-Alzheimer dementias, such as vascular dementia (VaD), frontotemporal dementia (FTD), dementia with Lewy bodies (DLB), and Parkinson disease dementia (PDD), might differentially affect fitness to drive.

DESIGN

To examine the effects of severity and type of dementia on driving fitness, we conducted a systematic review with qualitative narrative synthesis, involving different driving outcomes in different forms and stages of dementia.

SETTING

Literature research included MEDLINE and PsycINFO databases with a focus on the most relevant and recent publications on the topic.

PARTICIPANTS

The population of interest included older drivers in different stages of ADD and different forms of non-Alzheimer dementias (VaD, FTD, DLB, and PDD).

MEASUREMENTS

Narrative description of driving outcomes in the population of interest.

RESULTS

Overall, previous studies suggest that driving fitness is severely impaired in moderate and severe dementia, irrespective of the type of dementia. In milder disease stages, fitness to drive appears to be more severely impaired in non-Alzheimer dementias than in ADD, since the non-Alzheimer syndromes are not only associated with driving-relevant cognitive but noncognitive risk factors, such as behavioral or motor symptoms.

CONCLUSIONS

Based on these findings, practical recommendations are presented, including a risk evaluation for driving safety, depending on severity and type of different dementia syndromes. J Am Geriatr Soc 67:2186-2192, 2019.

摘要

背景/目的:大多数形式的痴呆症都与进行性认知和非认知障碍有关,这些障碍可能严重影响驾驶能力。然而,在单一病例中是否仍然能够安全驾驶,通常很难确定,并且可能取决于各自痴呆症综合征的严重程度和类型。特别是在疾病的早期阶段,阿尔茨海默病痴呆症(ADD)和不同类型的非阿尔茨海默痴呆症,如血管性痴呆症(VaD)、额颞叶痴呆症(FTD)、路易体痴呆症(DLB)和帕金森病痴呆症(PDD),可能会对驾驶能力产生不同的影响。

设计

为了研究痴呆症的严重程度和类型对驾驶能力的影响,我们进行了系统评价,采用了定性叙述性综合分析方法,涉及不同形式和阶段的痴呆症中的不同驾驶结果。

设置

文献研究包括 MEDLINE 和 PsycINFO 数据库,重点关注与该主题相关的最新出版物。

参与者

研究对象包括处于不同阶段的 ADD 和不同类型的非阿尔茨海默痴呆症(VaD、FTD、DLB 和 PDD)的老年驾驶员。

测量

对研究对象人群中的驾驶结果进行叙述性描述。

结果

总体而言,先前的研究表明,无论痴呆症的类型如何,中度和重度痴呆症患者的驾驶能力都严重受损。在疾病的早期阶段,与阿尔茨海默病相比,非阿尔茨海默痴呆症患者的驾驶能力似乎受损更为严重,因为非阿尔茨海默病综合征不仅与驾驶相关的认知风险因素有关,还与非认知风险因素有关,例如行为或运动症状。

结论

基于这些发现,提出了实际建议,包括根据不同痴呆症综合征的严重程度和类型,对驾驶安全进行风险评估。美国老年医学会 67:2186-2192, 2019.

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